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SMS2 / SGMS2

sphingomyelin synthase 2

Sphingomyelin synthases synthesize the sphingolipid, sphingomyelin, through transfer of the phosphatidyl head group, phosphatidylcholine, on to the primary hydroxyl of ceramide. The reaction is bidirectional depending on the respective levels of the sphingolipid and ceramide. Plasma membrane SMS2 can also convert phosphatidylethanolamine (PE) to ceramide phosphatidylethanolamine (CPE). Major form in liver. Required for cell growth in certain cell types. Regulator of cell surface levels of ceramide, an important mediator of signal transduction and apoptosis. Regulation of sphingomyelin (SM) levels at the cell surface affects insulin sensitivity.

Gene Name: sphingomyelin synthase 2
Synonyms: SGMS2, SM synthase, Sphingomyelin synthase 2, SMS2
Target Sequences: NM_152621 Q8NHU3 Q8NHU3

☰ Filters
Antibodies (15)
Proteins (8)
Over-Expression Lysate (6)
Primary (15)
Recombinant (2)
SMS2 / SGMS2 (23)
Human (15)
Mouse (7)
Rat (6)
Bat (6)
Bovine (6)
Chimpanzee (6)
Dog (6)
Gibbon (6)
Guinea pig (6)
Hamster (6)
Horse (6)
Monkey (6)
Pig (6)
Rabbit (6)
IHC (1)
WB (11)
ELISA (5)
rabbit (15)
IgG (14)
polyclonal pc (15)
Biotin Conjugated (3)
FITC Conjugated (3)
HRP Conjugated (3)
Unconjugated (6)
aa71-120 (8)
aa338-365 (1)
No (23)
GST (1)
GST, N-terminus (1)
Myc-DDK (Flag) (6)
Human (5)
293T Cells (3)
HEK 293 Cells (3)
Wheat Germ Extract (2)
Purified (1)
SMS2 / SGMS2 Antibody - Western blot of SGMS2 Antibody in HepG2 cell line lysates (35 ug/lane). SGMS2 (arrow) was detected using the purified antibody.
Select
SMS2 / SGMS2 Rabbit anti-Human Polyclonal (aa338-365) Antibody
Mouse, Human
WB
Unconjugated
400 µl/$393
SMS2 / SGMS2 Antibody - SGMS2 antibody Western blot of Fetal Heart lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
SMS2 / SGMS2 Rabbit anti-Human Polyclonal (aa71-120) Antibody
Human
WB
Unconjugated
100 µl/$424
SMS2 / SGMS2 Antibody - SGMS2 antibody Western blot of Fetal Heart lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
SMS2 / SGMS2 Rabbit anti-Human Polyclonal (aa71-120) (HRP) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Pig, Horse, Bat, Rat, Hamster, Chimpanzee, Gibbon, Human, Monkey
WB
HRP Conjugated
100 µl/$469
SMS2 / SGMS2 Antibody - SGMS2 antibody Western blot of Fetal Heart lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
SMS2 / SGMS2 Rabbit anti-Human Polyclonal (aa71-120) (Biotin) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Pig, Horse, Bat, Rat, Hamster, Chimpanzee, Gibbon, Human, Monkey
WB
Biotin Conjugated
100 µl/$469
SMS2 / SGMS2 Antibody - SGMS2 antibody Western blot of Fetal Heart lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
SMS2 / SGMS2 Rabbit anti-Human Polyclonal (aa71-120) (FITC) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Pig, Horse, Bat, Rat, Hamster, Chimpanzee, Gibbon, Human, Monkey
WB
FITC Conjugated
100 µl/$469
SMS2 / SGMS2 Antibody - Fig 1. Western blot on human brain lysate (10 ug/lane) using Sphingomyelin Synthase 2 antibody to Sphingomyelin Synthase 2 (0.5 ug/ml). Lane A] 1 ug/ml antibody alone, lane B] antibody plus 3 ug blocking peptide. Blot was developed with Pierce Super System West Femto - 1 minute exposure. Fig 2. Human kidney section stained with anti-SMS-2 antibody at 2 ug/ml. Anti-rabbit Ig H+L HRP conjugate (5 ug/ml) without antigen retrieval.
Select
SMS2 / SGMS2 Rabbit anti-Human Polyclonal Antibody
Human
IHC, WB
Unconjugated
100 µg/$466
SMS2 / SGMS2 Antibody - Western blot on human brain lysate (10 ug/lane) using X2059P antibody to Sphingomyelin Synthase 2 (0.5 ug/ml). Lane A] 1 ug/ml antibody alone, lane B] antibody plus 3 ug blocking peptide. Blot was developed with Pierce Super System West Femto - 1 minute exposure.
Select
SMS2 / SGMS2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$572
SMS2 / SGMS2 Antibody - IHC image of SGMS2 Antibody diluted at 1:600 and staining in paraffin-embedded human appendix tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
Select
SMS2 / SGMS2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA
Unconjugated
50 µg/$294; 100 µg/$360
Select
SMS2 / SGMS2 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA
HRP Conjugated
50 µg/$294; 100 µg/$360
Select
SMS2 / SGMS2 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA
Biotin Conjugated
50 µg/$294; 100 µg/$360
Select
SMS2 / SGMS2 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA
FITC Conjugated
50 µg/$294; 100 µg/$360
SMS2 / SGMS2 Antibody - SGMS2 antibody Western blot of 293T cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
SMS2 / SGMS2 Rabbit anti-Human Polyclonal (aa71-120) Antibody
Human
WB
Unconjugated
100 µl/$424
SMS2 / SGMS2 Antibody - SGMS2 antibody Western blot of 293T cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
SMS2 / SGMS2 Rabbit anti-Human Polyclonal (aa71-120) (HRP) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Pig, Horse, Bat, Rat, Hamster, Chimpanzee, Gibbon, Human, Monkey
WB
HRP Conjugated
100 µl/$469
SMS2 / SGMS2 Antibody - SGMS2 antibody Western blot of 293T cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
SMS2 / SGMS2 Rabbit anti-Human Polyclonal (aa71-120) (Biotin) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Pig, Horse, Bat, Rat, Hamster, Chimpanzee, Gibbon, Human, Monkey
WB
Biotin Conjugated
100 µl/$469
SMS2 / SGMS2 Antibody - SGMS2 antibody Western blot of 293T cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
SMS2 / SGMS2 Rabbit anti-Human Polyclonal (aa71-120) (FITC) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Pig, Horse, Bat, Rat, Hamster, Chimpanzee, Gibbon, Human, Monkey
WB
FITC Conjugated
100 µl/$469
SMS2 / SGMS2 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
Select
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
SMS2 / SGMS2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
42.1 kDa
20 µg/$150
SMS2 / SGMS2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
42.1 kDa
20 µg/$150
SMS2 / SGMS2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
42.1 kDa
20 µg/$150
SMS2 / SGMS2 Protein - 12.5% SDS-PAGE of human MGC26963 stained with Coomassie Blue
Select
Wheat Germ Extract
GST
68.7 kDa
2 µg/$439
SMS2 / SGMS2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
42.1 kDa
100 µg/$494
SMS2 / SGMS2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
42.1 kDa
100 µg/$494
SMS2 / SGMS2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
42.1 kDa
100 µg/$494
Viewing 1-23 of 23 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).