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Anti-SMG1 / ATX Antibody (aa1000-1050) LS-C89135


Wt. Vol. Conc. Price
100 µg - 1 mg/ml $545
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)

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Rabbit Polyclonal to Human SMG1 / ATX
Human, Mouse
Western blot, ELISA


Human SMG1 / ATX
Human, Mouse (tested or 100% immunogen sequence identity)
Immunoaffinity purified


  • Western blot (1:1000 - 1:2000)

Specificity and Use

SMG1 / ATX antibody was raised against the epitope recognized maps to a region between residues 1000 and 1050 of human PI-3-Kinase-related kinase SMG1 using the numbering given in TrEMBL entry Q96QV0 (GeneID 23049).
Species cross-reactivity: Human. Other species have not been tested. Reactivity with mouse SMG1 (entry Q8BWJ5) is expected owing to complete identity between this ortholog and human SMG1 at the site to which the epitope maps.
Suitable for use in ELISA and Western Blot. Western Blot: 1:1000-1:2000.


Tris-citrate/phosphate, pH 7 to 8
Long term: Add glycerol (40-50%) -20°C; Short term: +4°C
For research use only.

About SMG1 / ATX

Q96Q15 NM_015092 NP_055907.3

SMG1 Antibody, HSMG-1 Antibody, KIAA0421 Antibody, Lambda-interacting protein Antibody, LIP Antibody, SMG-1 Antibody

Serine/threonine protein kinase involved in both mRNA surveillance and genotoxic stress response pathways. Recognizes the substrate consensus sequence [ST]-Q. Plays a central role in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons by phosphorylating UPF1/RENT1. Recruited by release factors to stalled ribosomes together with SMG8 and SMG9 (forming the SMG1C protein kinase complex), and UPF1 to form the transient SURF (SMG1-UPF1-eRF1-eRF3) complex.

Requested From: United States
Date Requested: 10/22/2016

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