The Immunohistochemistry Antibody Company
|Human, Mouse (tested or 100% immunogen sequence identity)|
|SMC4 antibody was raised against a synthetic peptide, which represented a portion of human structural maintenance of chromosomes 4 encoded within exons 11 and 12 (LocusLink ID 10051). According to Swiss-Prot entry Q9NTJ3, the peptide is within the flexible hinge domain.|
|Specific for human SMC4 protein. Species cross-reactivity: reacts with human. Other species have not been tested. Reactivity with mouse is likely owing to complete sequence homology between mouse sequence and the peptide used as the immunogen for this ant|
|Suitable for use in Western Blot.|
|Long term: Add glycerol (40-50%) -20°C; Short term: +4°C|
|For research use only.|
SMC4 Antibody, HCAP-C Antibody, SMC protein 4 Antibody, SMC4L1 Antibody, SMC-4 Antibody, XCAP-C homolog Antibody, CAP-C Antibody, CAPC AntibodyCentral component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.