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Anti-SMC1A / SMC1 Antibody (phospho-Ser957) LS-C43029

Note: This antibody replaces LS-C91805


Wt. Vol. Conc. Price
100 µg - 1 mg/ml Unavailable

Most Popular SMC1A / SMC1 Antibodies

Anti-SMC1A / SMC1 Antibody LS-C91803
Rabbit Polyclonal to Human SMC1A / SMC1
Human, Mouse, Xenopus
Immunofluorescence, Western blot, Immunoprecipitation
Anti-SMC1A / SMC1 Antibody (clone 1B9) IHC-plus™ LS-B5432
Mouse Monoclonal [clone 1B9] (IgG1,k) to Human SMC1A / SMC1
IHC - Paraffin, Western blot, ELISA
Immunohistochemistry Image
Anti-SMC1A / SMC1 Antibody (phospho-Ser966) LS-C286292
Rabbit Polyclonal (IgG) to Human SMC1A / SMC1
Human, Mouse
IHC - Paraffin, Immunofluorescence
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal (IgG) to Human SMC1A / SMC1
Western blot, Immunoprecipitation


Human SMC1A / SMC1
Human (tested or 100% immunogen sequence identity)
IgG Polyclonal


  • Western blot (1:200 - 1:2000)
  • Immunoprecipitation

Specificity and Use

SMC1A / SMC1 antibody was raised against phosphorylated synthetic peptide corresponding to a region within human SMC1 (locus link ID 5884) around serine 957. ( pSer957 ).
Recognizes human structural maintenance of chromosomes-1 (SMC1) which is phosphorylated at Ser957. SMC1 forms a heterodimer with SMC3, and is involved in sister chromatid cohesion and in DNA recombination and repair. SMC1 can be phosphorylated by ATM on serines 957 and 966 in vitro and in vivo in response to ionizing radiation. SMC1 also acts as a downstream effector in the ATM/NBS1 pathway of S-phase checkpoint.
Western Blot: LS-C43029 detects a band of approximately 150 kD in Hela cell lysates following treatment with 10 Gy ionizing radiation.


Tris-citrate/phosphate, pH 7.5, 0.09% sodium azide.
For research use only.

About SMC1A / SMC1

Q14683 NM_006306 NP_006297.2

SMC1A Antibody, CDLS2 Antibody, DXS423E Antibody, KIAA0178 Antibody, SB1.8 Antibody, SMC protein 1A Antibody, SMC1 Antibody, SMC1L1 Antibody, SMC-1-alpha Antibody, SMC-1A Antibody, SMCB Antibody

Proper cohesion of sister chromatids is a prerequisite for the correct segregation of chromosomes during cell division. The cohesin multiprotein complex is required for sister chromatid cohesion. This complex is composed partly of two structural maintenance of chromosomes (SMC) proteins, SMC3 and either SMC1B or the protein encoded by this gene. Most of the cohesin complexes dissociate from the chromosomes before mitosis, although those complexes at the kinetochore remain.

Western blot

Western blot
Detection of human phospho-SMC1 (pSER957) in whole cell lysates from HeLa cells subjected to 10Gy gamma irradiation or mock irradiated. Lysate was subsequently treated with calf alkaline phosphatase (CIP) of left untreated as indicated by Western Blotting with Rabbit anti-phospho-SMC1 (pSER957) (LS-C43029).

Requested From: 
Date Requested: 3/29/2017

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