SMARCC1 / SWI3

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1

Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). May stimulate the ATPase activity of the catalytic subunit of the complex. Also involved in vitamin D-coupled transcription regulation via its association with the WINAC complex, a chromatin-remodeling complex recruited by vitamin D receptor (VDR), which is required for the ligand-bound VDR-mediated transrepression of the CYP27B1 gene. Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth.

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Products

Antibodies (18)

Proteins (4)

ELISA Kits (1)

Type

Primary (18)

Recombinant (4)

Sandwich (1)

Target

SMARCC1 / SWI3 (23)

Reactivity

Human (19)

Mouse (5)

Rat (6)

Chimpanzee (3)

Gibbon (3)

Guinea pig (3)

Monkey (3)

Application

IHC (4)

IHC-P (3)

WB (17)

ChIP-Seq (1)

ChrIP (2)

ELISA (3)

ICC (1)

IF (3)

IP (7)

Peptide-ELISA (1)

Host

rabbit (16)

mouse (2)

Isotype

IgG (11)

IgG1 (1)

Clonality

monoclonal mc (2)

polyclonal pc (16)

Format

96-Well Strip Plate (1)

Biotin Conjugated (1)

FITC Conjugated (1)

HRP Conjugated (1)

Preservative Free (1)

Unconjugated (15)

Epitope

aa828-877 (4)

aa963-997 (2)

aa1055-C-term (1)

aa300-350 (1)

aa750-800 (1)

aa80-320 (1)

Publications

No (23)

Sample Type

Cell Lysates (1)

Tissue Homogenates (1)

Tag

6His, N-terminus (1)

GST, N-terminus (1)

His-SUMO (1)

Myc-DDK (Flag) (1)

Species

Human (4)

Source

Baculovirus (1)

E. coli (1)

HEK 293 Cells (1)

Wheat Germ Extract (1)

Purification

Purified (1)

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SMARCC1 / SWI3 Antibody LS-C335636

Antibody:

SMARCC1 / SWI3 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ChIP-Seq, IF, IHC, IP, WB

Format:

Unconjugated

Price:

20 µl/$287; 50 µl/$341; 100 µl/$431; 200 µl/$539

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SMARCC1 / SWI3 Antibody LS-C393582

Antibody:

SMARCC1 / SWI3 Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$391

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SMARCC1 / SWI3 Antibody (Preservative Free) LS-C815044

Antibody:

SMARCC1 / SWI3 Rabbit anti-Human Polyclonal (Preservative Free) Antibody

Reactivity:

Human

Applications:

ICC, IF, IHC-P, WB

Format:

Unconjugated, Preservative Free

Price:

100 µl/$412

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SMARCC1 / SWI3 Antibody LS-C755027

Antibody:

SMARCC1 / SWI3 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IP, WB

Format:

Unconjugated

Price:

100 µg/$341

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SMARCC1 / SWI3 Antibody LS-C482528

Antibody:

SMARCC1 / SWI3 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ChrIP, IHC, IHC-P, IP, WB

Format:

Unconjugated

Price:

50 µl/$286; 100 µl/$321; 200 µl/$386

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SMARCC1 / SWI3 Antibody LS-C341929

Antibody:

SMARCC1 / SWI3 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ChrIP, IF, WB

Format:

Unconjugated

Price:

50 µl/$356; 100 µl/$461

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SMARCC1 / SWI3 Antibody (aa80-320) LS-C378213

Antibody:

SMARCC1 / SWI3 Rabbit anti-Human Polyclonal (aa80-320) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P

Format:

Unconjugated

Price:

50 µl/$294; 100 µl/$360

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SMARCC1 / SWI3 Antibody LS-C814121

Antibody:

SMARCC1 / SWI3 Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µg/$332; 100 µg/$404; 200 µg/$505

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SMARCC1 / SWI3 Antibody (aa300-350) LS-C287849

Antibody:

SMARCC1 / SWI3 Rabbit anti-Human Polyclonal (aa300-350) Antibody

Reactivity:

Human

Applications:

IP, WB

Format:

Unconjugated

Price:

10 µl/$295; 100 µl/$514

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SMARCC1 / SWI3 Antibody (aa750-800) LS-C287850

Antibody:

SMARCC1 / SWI3 Rabbit anti-Human Polyclonal (aa750-800) Antibody

Reactivity:

Human

Applications:

IP, WB

Format:

Unconjugated

Price:

10 µl/$295; 100 µl/$514

Select

SMARCC1 / SWI3 Antibody (aa1055-C-term) LS-C287851

Antibody:

SMARCC1 / SWI3 Rabbit anti-Human Polyclonal (aa1055-C-term) Antibody

Reactivity:

Human

Applications:

IP, WB

Format:

Unconjugated

Price:

10 µl/$295; 100 µl/$514

Select

SMARCC1 / SWI3 Antibody LS-C484811

Antibody:

SMARCC1 / SWI3 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IP, WB

Format:

Unconjugated

Price:

100 µl/$412

Select

SMARCC1 / SWI3 Antibody (aa963-997) LS-C356647

Antibody:

SMARCC1 / SWI3 Rabbit anti-Human Polyclonal (aa963-997) Antibody

Reactivity:

Mouse, Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

400 µl/$393

Select

SMARCC1 / SWI3 Antibody (aa963-997) LS-C344476

Antibody:

SMARCC1 / SWI3 Rabbit anti-Mouse Polyclonal (aa963-997) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

400 µl/$393

Select

SMARCC1 / SWI3 Antibody (aa828-877) LS-C31762

Antibody:

SMARCC1 / SWI3 Rabbit anti-Human Polyclonal (aa828-877) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$397

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SMARCC1 / SWI3 Antibody (aa828-877, HRP) LS-C429327

Antibody:

SMARCC1 / SWI3 Rabbit anti-Human Polyclonal (aa828-877) (HRP) Antibody

Reactivity:

Guinea pig, Rat, Chimpanzee, Gibbon, Human, Monkey

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$442

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SMARCC1 / SWI3 Antibody (aa828-877, Biotin) LS-C429324

Antibody:

SMARCC1 / SWI3 Rabbit anti-Human Polyclonal (aa828-877) (Biotin) Antibody

Reactivity:

Guinea pig, Rat, Chimpanzee, Gibbon, Human, Monkey

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$442

Select

SMARCC1 / SWI3 Antibody (aa828-877, FITC) LS-C429325

Antibody:

SMARCC1 / SWI3 Rabbit anti-Human Polyclonal (aa828-877) (FITC) Antibody

Reactivity:

Guinea pig, Rat, Chimpanzee, Gibbon, Human, Monkey

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$442

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

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Human SMARCC1 / SWI3 Protein (Recombinant GST, N-terminus) (aa338-437) - LS-G60143

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human SMARCC1 / SWI3 Protein (Recombinant 6His, N-terminus) (aa449-669) - LS-G55979

Source:

Baculovirus

Tag:

6His, N-terminus

Price:

100 µg/$1,164; 20 µg/$475; 1 mg/$2,187

Select

Human SMARCC1 / SWI3 (Sandwich ELISA) ELISA Kit - LS-F55049

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Tissue Homogenates

Price:

1 Plate/$834

Select

Human SMARCC1 / SWI3 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G68238

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

122.7 kDa

Price:

20 µg/$1,107

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Human SMARCC1 / SWI3 Protein (Recombinant His-SUMO) (aa449-669) - LS-G21804

Source:

E. coli

Tag:

His-SUMO

Molecular Weight:

41.5 kD

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

Viewing 1-23 of 23 product results

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