SMARCA2 / BRM

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2

Transcriptional coactivator cooperating with nuclear hormone receptors to potentiate transcriptional activation. Also involved in vitamin D-coupled transcription regulation via its association with the WINAC complex, a chromatin-remodeling complex recruited by vitamin D receptor (VDR), which is required for the ligand-bound VDR-mediated transrepression of the CYP27B1 gene. Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth.

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Products

Antibodies (22)

Proteins (3)

Type

Primary (22)

Recombinant (3)

Target

SMARCA2 / BRM (25)

Reactivity

Human (22)

Mouse (11)

Rat (11)

Bat (6)

Bovine (7)

Chicken (6)

Dog (7)

Gibbon (6)

Guinea pig (6)

Hamster (6)

Horse (6)

Monkey (8)

Orangutan (6)

Pig (6)

Rabbit (6)

Xenopus (6)

Zebrafish (6)

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Application

IHC (5)

IHC-P (5)

WB (21)

ChrIP (4)

ELISA (6)

IF (1)

IP (3)

Peptide-ELISA (2)

Host

rabbit (21)

mouse (1)

Product Group

IHCPlus (1)

Isotype

IgG (14)

IgG2a,k (1)

Clonality

monoclonal mc (1)

polyclonal pc (21)

Clone

2D12 (1)

Format

Biotin Conjugated (3)

FITC Conjugated (3)

HRP Conjugated (3)

Unconjugated (13)

Epitope

aa58-107 (4)

aa68-117 (4)

aa700-1216 (4)

Internal (2)

Gly264 (1)

aa1-50 (1)

aa100-150 (1)

aa1325-1375 (1)

aa1328-1377 (1)

aa1387-1432 (1)

Publications

No (25)

Tag

6His, N-terminus (1)

GST, N-terminus (1)

His-SUMO (1)

Species

Human (3)

Source

E. coli (1)

Wheat Germ Extract (1)

Yeast (1)

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IHC-plus™ SMARCA2 / BRM Antibody (aa100-150) LS-B13997

(4.0) Rating

Antibody:

SMARCA2 / BRM Rabbit anti-Human Polyclonal (aa100-150) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, IP, WB

Format:

Unconjugated

Price:

50 µl/$460

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SMARCA2 / BRM Antibody (clone 2D12) LS-C198223

Antibody:

SMARCA2 / BRM Mouse anti-Human Monoclonal (2D12) Antibody

Reactivity:

Human

Applications:

ELISA, IF, WB

Format:

Unconjugated

Price:

100 µg/$423

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SMARCA2 / BRM Antibody (aa58-107) LS-C30062

Antibody:

SMARCA2 / BRM Rabbit anti-Human Polyclonal (aa58-107) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$424

Select

SMARCA2 / BRM Antibody (aa58-107, HRP) LS-C431220

Antibody:

SMARCA2 / BRM Rabbit anti-Human Polyclonal (aa58-107) (HRP) Antibody

Reactivity:

Xenopus, Chicken, Zebrafish, Pig, Horse, Rat, Hamster, Bat, Bovine, Rabbit, Mouse, Dog, Guinea pig, Human, Monkey, Gibbon, Orangutan

Applications:

IHC, IHC-P, WB

Format:

HRP Conjugated

Price:

100 µl/$469

Select

SMARCA2 / BRM Antibody (aa58-107, Biotin) LS-C431219

Antibody:

SMARCA2 / BRM Rabbit anti-Human Polyclonal (aa58-107) (Biotin) Antibody

Reactivity:

Xenopus, Chicken, Zebrafish, Pig, Horse, Rat, Hamster, Bat, Bovine, Rabbit, Mouse, Dog, Guinea pig, Human, Monkey, Gibbon, Orangutan

Applications:

IHC, IHC-P, WB

Format:

Biotin Conjugated

Price:

100 µl/$469

Select

SMARCA2 / BRM Antibody (aa58-107, FITC) LS-C431218

Antibody:

SMARCA2 / BRM Rabbit anti-Human Polyclonal (aa58-107) (FITC) Antibody

Reactivity:

Xenopus, Chicken, Zebrafish, Pig, Horse, Rat, Hamster, Bat, Bovine, Rabbit, Mouse, Dog, Guinea pig, Human, Monkey, Gibbon, Orangutan

Applications:

IHC, IHC-P, WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

SMARCA2 / BRM Antibody (Internal) LS-C386800

Antibody:

SMARCA2 / BRM Rabbit anti-Human Polyclonal (Internal) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

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SMARCA2 / BRM Antibody (aa1328-1377) LS-C199778

Antibody:

SMARCA2 / BRM Rabbit anti-Human Polyclonal (aa1328-1377) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

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Human SMARCA2 / BRM Protein (Recombinant 6His, N-terminus) (aa700-1216) - LS-G23136

Source:

Yeast

Tag:

6His, N-terminus

Molecular Weight:

61.7 kD

Price:

100 µg/$446; 20 µg/$336; 1 mg/$1,460

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SMARCA2 / BRM Antibody (aa1325-1375) LS-C287846

Antibody:

SMARCA2 / BRM Rabbit anti-Human Polyclonal (aa1325-1375) Antibody

Reactivity:

Human

Applications:

IP, WB

Format:

Unconjugated

Price:

10 µl/$295; 100 µl/$514

Select

SMARCA2 / BRM Antibody LS-C809822

Antibody:

SMARCA2 / BRM Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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SMARCA2 / BRM Antibody (aa1387-1432) LS-C313685

Antibody:

SMARCA2 / BRM Rabbit anti-Human Polyclonal (aa1387-1432) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

50 µl/$321; 100 µl/$403

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Human SMARCA2 / BRM Protein (Recombinant His-SUMO) (aa700-1216) - LS-G21196

Source:

E. coli

Tag:

His-SUMO

Molecular Weight:

75.7 kD

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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SMARCA2 / BRM Antibody (aa700-1216) LS-C370344

Antibody:

SMARCA2 / BRM Rabbit anti-Human Polyclonal (aa700-1216) Antibody

Reactivity:

Human

Applications:

ChrIP, ELISA

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

Select

SMARCA2 / BRM Antibody (aa700-1216, HRP) LS-C370343

Antibody:

SMARCA2 / BRM Rabbit anti-Human Polyclonal (aa700-1216) (HRP) Antibody

Reactivity:

Human

Applications:

ChrIP, ELISA, WB

Format:

HRP Conjugated

Price:

50 µg/$294; 100 µg/$360

Select

SMARCA2 / BRM Antibody (aa700-1216, Biotin) LS-C370346

Antibody:

SMARCA2 / BRM Rabbit anti-Human Polyclonal (aa700-1216) (Biotin) Antibody

Reactivity:

Human

Applications:

ChrIP, ELISA, WB

Format:

Biotin Conjugated

Price:

50 µg/$294; 100 µg/$360

Select

SMARCA2 / BRM Antibody (aa700-1216, FITC) LS-C370342

Antibody:

SMARCA2 / BRM Rabbit anti-Human Polyclonal (aa700-1216) (FITC) Antibody

Reactivity:

Human

Applications:

ChrIP, ELISA, WB

Format:

FITC Conjugated

Price:

50 µg/$294; 100 µg/$360

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

SMARCA2 / BRM Antibody (aa1-50) LS-C287844

Antibody:

SMARCA2 / BRM Rabbit anti-Human Polyclonal (aa1-50) Antibody

Reactivity:

Human

Applications:

IP, WB

Format:

Unconjugated

Price:

10 µl/$295; 100 µl/$514

Select

SMARCA2 / BRM Antibody (Gly264) LS-C191295

Antibody:

SMARCA2 / BRM Rabbit anti-Human Polyclonal (Gly264) Antibody

Reactivity:

Dog, Human, Monkey

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$688

Select

SMARCA2 / BRM Antibody (aa68-117) LS-C201291

Antibody:

SMARCA2 / BRM Rabbit anti-Human Polyclonal (aa68-117) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

Select

SMARCA2 / BRM Antibody (aa68-117, HRP) LS-C430664

Antibody:

SMARCA2 / BRM Rabbit anti-Human Polyclonal (aa68-117) (HRP) Antibody

Reactivity:

Xenopus, Chicken, Zebrafish, Pig, Horse, Rat, Hamster, Bat, Bovine, Rabbit, Mouse, Dog, Guinea pig, Human, Monkey, Gibbon, Orangutan

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

Select

SMARCA2 / BRM Antibody (aa68-117, Biotin) LS-C430661

Antibody:

SMARCA2 / BRM Rabbit anti-Human Polyclonal (aa68-117) (Biotin) Antibody

Reactivity:

Xenopus, Chicken, Zebrafish, Pig, Horse, Rat, Hamster, Bat, Bovine, Rabbit, Mouse, Dog, Guinea pig, Human, Monkey, Gibbon, Orangutan

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

Select

SMARCA2 / BRM Antibody (aa68-117, FITC) LS-C430662

Antibody:

SMARCA2 / BRM Rabbit anti-Human Polyclonal (aa68-117) (FITC) Antibody

Reactivity:

Xenopus, Chicken, Zebrafish, Pig, Horse, Rat, Hamster, Bat, Bovine, Rabbit, Mouse, Dog, Guinea pig, Human, Monkey, Gibbon, Orangutan

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

SMARCA2 / BRM Antibody (Internal) LS-C352855

Antibody:

SMARCA2 / BRM Rabbit anti-Human Polyclonal (Internal) Antibody

Reactivity:

Mouse, Bovine, Rat, Human, Monkey

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$299

Select

Human SMARCA2 / BRM Protein (Recombinant GST, N-terminus) (aa659-735) - LS-G60138

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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