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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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SMAD6 Antibody LS‑C89113
Antibody
SMAD6 antibody LS-C89113 is an unconjugated rabbit polyclonal antibody to SMAD6 from human, mouse, rat and other species. Validated for ELISA and WB.
Catalog
Size
Price
LS-C89113-100
100 µg (1 mg/ml)
Unavailable

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Product Description

SMAD6 antibody LS-C89113 is an unconjugated rabbit polyclonal antibody to SMAD6 from human, mouse, rat and other species. Validated for ELISA and WB.
About SMAD6
Acts as a mediator of TGF-beta and BMP antiflammatory activity. Suppresses IL1R-TLR signaling through its direct interaction with PEL1, preventing NF-kappa-B activation, nuclear transport and NF-kappa-B-mediated expression of proinflammatory genes. May block the BMP-SMAD1 signaling pathway by competing with SMAD4 for receptor-activated SMAD1-binding. Binds to regulatory elements in target promoter regions. O43541 NM_005585 NP_005576.3

SMAD6 Antibody, AOVD2 Antibody, HSMAD6 Antibody, HsT17432 Antibody, SMAD 6 Antibody, MADH7 Antibody, Mothers against DPP homolog 6 Antibody, SMAD family member 6 Antibody, MAD homolog 6 Antibody, MADH6 Antibody


Specifications

Target
Human SMAD6
Host
Rabbit
Reactivity
Human, Monkey, Mouse, Rat (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • Western blot (1:1000 - 1:2000)
  • ELISA
Specificity
A 52kD band is observed. Species cross-reactivity: Human, Monkey, Mouse, Rat.
Usage
Suitable for use in ELISA and Western Blot. Western Blot: 1:1000-1:2000.
Presentation
PBS, 0.05% sodium azide
Storage
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/20/2018

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