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Anti-SMAD3 Antibody (phospho-Ser425) LS-C205286


Wt. Vol. Conc. Price
- 50 µl 1 mg/ml $285
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)

Most Popular SMAD3 Antibodies

Anti-SMAD3 Antibody (phospho-Ser423/Ser425) IHC-plus™ LS-B64
Rabbit Polyclonal to Human SMAD3
Human, Mouse, Rat, Bovine, Pig, Chicken, Xenopus, Zebrafish
IHC - Paraffin, Immunofluorescence, Western blot, Flow Cytometry, ELISA
Immunohistochemistry Image
Anti-SMAD3 Antibody (C-Terminus) LS-C46894
Rabbit Polyclonal to Human SMAD3
Western blot, ELISA
Anti-SMAD3 Antibody (aa100-150) IHC-plus™ LS-B2064
Rabbit Polyclonal to Human SMAD3
Human, Monkey, Mouse, Rat, Bovine, Dog, Pig, Macaque
IHC - Paraffin, Western blot
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal to Human SMAD3
Human, Mouse, Rat
IHC - Paraffin, Western blot


Human SMAD3
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
Immunoaffinity purified


  • IHC - Paraffin (1:50 - 1:100)
  • Western blot (1:500 - 1:1000)

Specificity and Use

SMAD3 antibody was raised against peptide sequence around phosphorylation site of serine 425 (C-S-S-V-S (p)) of human Smad3.
The antibody detects endogenous levels of Smad3 only when phosphorylated at serine 425.


PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only.

About SMAD3

P84022 NM_005902 NP_005893.1

SMAD3 Antibody, HSPC193 Antibody, HMAD-3 Antibody, HsT17436 Antibody, LDS1C Antibody, LDS3 Antibody, Mad homolog JV15-2 Antibody, MAD3 Antibody, MADH3 Antibody, Mothers against DPP homolog 3 Antibody, JV15-2 Antibody, SMA- and MAD-related protein 3 Antibody, SMAD family member 3 Antibody, MAD homolog 3 Antibody, HSMAD3 Antibody, Mad protein homolog Antibody, SMAD 3 Antibody

Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD3/SMAD4 complex, activates transcription. Also can form a SMAD3/SMAD4/JUN/FOS complex at the AP-1/SMAD site to regulate TGF-beta-mediated transcription.


Immunohistochemistry of paraffin-embedded human breast carcinoma tissue using Smad3 (Phospho-Ser425) antibody (left) or the same antibody preincubated with blocking peptide (right).

Western blot

Western blot
Western blot of extracts from HeLa cells untreated or treated with EGF using Smad3 (Phospho-Ser425) antibody.

Requested From: United States
Date Requested: 10/21/2016

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