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SLC9A3R1 / NHERF1 / EBP50
solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. Necessary for recycling of internalized ADRB2. Was first known to play a role in the regulation of the activity and subcellular location of SLC9A3. Necessary for cAMP-mediated phosphorylation and inhibition of SLC9A3. May enhance Wnt signaling. May participate in HTR4 targeting to microvilli (By similarity). Involved in the regulation of phosphate reabsorption in the renal proximal tubules. Involved in sperm capacitation. May participate in the regulation of the chloride and bicarbonate homeostasis in spermatozoa.
| Gene Name: | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 |
| Family/Subfamily: | Transporter , Monovalent cation:proton antiporter-1 |
| Synonyms: | SLC9A3R1, EBP50, NPHLOP2, NHERF, NHERF-1, NHERF1 |
| Target Sequences: | NM_004252 NP_004243.1 O14745 |
Publications (2)
1
Cell cycle dependent association of EBP50 with protein phosphatase 2A in endothelial cells. Boratk A, Gergely P, Csortos C. PloS one. 2012 7:e35595.
[PubMed:22523604]
[PMC:PMC3327649]
Related Antibodies: LS-C161280.
2
PTEN phosphatase-independent maintenance of glandular morphology in a predictive colorectal cancer model system. Jagan IC, Deevi RK, Fatehullah A, Topley R, Eves J, Stevenson M, Loughrey M, Arthur K, Campbell FC. Neoplasia (New York, N.Y.). 2013 15:1218-30. (WB; Human)
[PubMed:24348097]
[PMC:PMC3858899]
Related Antibodies: LS-B1873.
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Antibodies
(32)
Proteins
(5)
Type
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Primary
(32)
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Target
SLC9A3R1 / NHERF1 / EBP50
(37)
Reactivity
Human
(32)
Mouse
(12)
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(6)
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(3)
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(3)
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(6)
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(3)
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(3)
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(3)
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(6)
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(3)
Application
IHC
(7)
IHC-P
(5)
WB
(32)
Flo
(7)
ELISA
(10)
ICC
(1)
IF
(1)
IP
(7)
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(1)
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rabbit
(28)
mouse
(4)
Product Group
IHCPlus
(3)
PathPlus Other
(1)
Isotype
IgG
(16)
IgG2a,k
(1)
IgG2b
(3)
Clonality
monoclonal mc
(4)
polyclonal pc
(28)
Clone
2B7
(1)
EBP-10
(3)
Format
APC Conjugated
(1)
Azide-free
(1)
Biotin Conjugated
(4)
Concentrated
(1)
FITC Conjugated
(3)
HRP Conjugated
(3)
PE Conjugated
(1)
Unconjugated
(20)
Epitope
aa168-197
(7)
N-Terminus
(4)
aa287-336
(4)
C-Terminus
(2)
Ala140
(1)
aa225-275
(1)
aa275-325
(1)
aa325-358
(1)
Publications
No
(35)
Yes
(2)
Tag
GST
(1)
GST, N-terminus
(1)
Myc-DDK (Flag)
(3)
Species
Human
(4)
Source
293T Cells
(1)
HEK 293 Cells
(2)
Wheat Germ Extract
(2)
Purification
Purified
(1)
SLC9A3R1 / NHERF1 / EBP50 Mouse anti-Human Monoclonal (EBP-10) Antibody
Human
IHC, IHC-P, IP, WB
Unconjugated
0.05 mg/$460
SLC9A3R1 / NHERF1 / EBP50 Rabbit anti-Mouse Polyclonal (C-Terminus) Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
0.1 mg/$379
SLC9A3R1 / NHERF1 / EBP50 Rabbit anti-Human Polyclonal (aa168-197) Antibody
Human
Flo, WB
Unconjugated
400 µl/$393
SLC9A3R1 / NHERF1 / EBP50 Mouse anti-Human Monoclonal (2B7) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$460
SLC9A3R1 / NHERF1 / EBP50 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IHC, IHC-P, IP, WB
Unconjugated
50 µg/$485
SLC9A3R1 / NHERF1 / EBP50 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$832
SLC9A3R1 / NHERF1 / EBP50 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
IHC-P, WB
Unconjugated
100 µl/$485
SLC9A3R1 / NHERF1 / EBP50 Rabbit anti-Human Polyclonal Antibody
Human
ICC, IF, WB
Unconjugated
100 µl/$688
SLC9A3R1 / NHERF1 / EBP50 Rabbit anti-Human Polyclonal (aa168-197) Antibody
Human
ELISA, Flo, WB
Unconjugated
200 µl/$734
SLC9A3R1 / NHERF1 / EBP50 Rabbit anti-Human Polyclonal (aa168-197) (Biotin) Antibody
Human
ELISA, Flo, WB
Biotin Conjugated
200 µl/$952
SLC9A3R1 / NHERF1 / EBP50 Rabbit anti-Human Polyclonal (aa168-197) (FITC) Antibody
Human
ELISA, Flo, WB
FITC Conjugated
200 µl/$952
SLC9A3R1 / NHERF1 / EBP50 Rabbit anti-Human Polyclonal (aa168-197) (APC) Antibody
Human
ELISA, Flo, WB
APC Conjugated
200 µl/$952
SLC9A3R1 / NHERF1 / EBP50 Rabbit anti-Human Polyclonal (aa168-197) (PE) Antibody
Human
ELISA, Flo, WB
PE Conjugated
200 µl/$952
SLC9A3R1 / NHERF1 / EBP50 Rabbit anti-Human Polyclonal (aa168-197) (Azide-free) (HRP) Antibody
Human
ELISA, Flo, WB
HRP Conjugated, Azide-free
200 µl/$952
SLC9A3R1 / NHERF1 / EBP50 Rabbit anti-Human Polyclonal (aa275-325) Antibody
Mouse, Human
IHC, IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
SLC9A3R1 / NHERF1 / EBP50 Rabbit anti-Human Polyclonal (aa325-358) Antibody
Human
IHC, IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
SLC9A3R1 / NHERF1 / EBP50 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
SLC9A3R1 / NHERF1 / EBP50 Mouse anti-Human Monoclonal (EBP-10) Antibody
Human
IHC-P, IP, WB
Unconjugated
100 µg/$493
SLC9A3R1 / NHERF1 / EBP50 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$357
SLC9A3R1 / NHERF1 / EBP50 Mouse anti-Human Monoclonal (Concentrated) (EBP-10) Antibody
Human
IP, WB
Unconjugated, Concentrated
0.1 mg/$545
SLC9A3R1 / NHERF1 / EBP50 Rabbit anti-Human Polyclonal (Biotin) Antibody
Mouse, Human
IHC, WB
Biotin Conjugated
100 µl/$1,007
SLC9A3R1 / NHERF1 / EBP50 Rabbit anti-Human Polyclonal (aa225-275) Antibody
Human
IP, WB
Unconjugated
100 µl/$456
SLC9A3R1 / NHERF1 / EBP50 Rabbit anti-Human Polyclonal (Ala140) Antibody
Human
WB
Unconjugated
100 µl/$688
SLC9A3R1 / NHERF1 / EBP50 Rabbit anti-Human Polyclonal (aa287-336) Antibody
Human
WB
Unconjugated
100 µl/$424
SLC9A3R1 / NHERF1 / EBP50 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
50 µl/$286; 100 µl/$321
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product results
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