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Anti-SLC9A3R1 / NHERF1 / EBP50 Antibody LS-C44851


Wt. Vol. Conc. Price
100 µg - 1 mg/ml $305
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)

Most Popular SLC9A3R1 / NHERF1 / EBP50 Antibodies

Anti-SLC9A3R1 / NHERF1 / EBP50 Antibody (clone EBP-10) IHC-plus™ LS-B1873
Mouse Monoclonal [clone EBP-10] (IgG2b) to Human SLC9A3R1 / NHERF1 / EBP50
IHC - Paraffin, Western blot, Immunoprecipitation, Inhibition
Immunohistochemistry Image
Anti-SLC9A3R1 / NHERF1 / EBP50 Antibody (C-Terminus, clone EPR5563) IHC-plus™ LS-B7499
Rabbit Monoclonal [clone EPR5563] to Human SLC9A3R1 / NHERF1 / EBP50
Human, Mouse, Rat
IHC - Paraffin, ICC, Immunofluorescence, Western blot, Immunoprecipitation, Flow Cytometry
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Mouse Monoclonal (IgG2b) to Human SLC9A3R1 / NHERF1 / EBP50
Western blot, Immunoprecipitation


Human SLC9A3R1 / NHERF1 / EBP50
Human (tested or 100% immunogen sequence identity)
IgG2b Monoclonal
Protein A purified


  • Western blot
  • Immunoprecipitation

Specificity and Use

SLC9A3R1 / NHERF1 / EBP50 antibody was raised against bacterially produced recombinant full length human EBP50.
Recognizes ezrin/radixin/moesin (ERM)-binding phosphoprotein of 50kD (EBP50) otherwise known as Na+/H+ exchanger regulatory factor (NHERF). EBP50 is a PDZ-containing cytoplasmic adaptor molecule, shown to be expressed in tissues containing polarized epithelia, namely small intestine, placenta, liver and kidney. The ERM family of membrane-cytoskeletal linking proteins act to maintain a regulated linkage between actin filaments (F-actin) and the plasma membrane. Studies have revealed that EBP50 is an important ERM binding partner, which interacts with the N-terminal FERM (four point one ERM) domain of ERM proteins, via its C-terminal domain. Immunofluorescence studies have revealed the co-localization of EBP50 with actin and ezrin, in the apical microvilli of epithelial cells and this role as binding partner has been further shown through the interaction of EBP50 with the transmembrane adaptor protein known as Protein Associated with Glycosphingolipid-enriched microdomains (PAG), in T cells. Other ligands which bind to the PDZ domains of EBP50, include beta-catenin, cystic fibrosis transmembrane conductance regulator and the type II Na/Pi cotransporter Npt2, implicating EBP50 in a diverse range of biological systems.
Western Blot: LS-C44851 detects a band of approximately 50 kD in Breast Carcinoma alpha Jurkat cell lysates.


PBS, pH 7.4, 0.09% sodium azide.
For research use only.

About SLC9A3R1 / NHERF1 / EBP50

O14745 NM_004252 NP_004243.1

SLC9A3R1 Antibody, EBP50 Antibody, NPHLOP2 Antibody, NHERF Antibody, NHERF-1 Antibody, NHERF1 Antibody

Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. Necessary for recycling of internalized ADRB2. Was first known to play a role in the regulation of the activity and subcellular location of SLC9A3. Necessary for cAMP-mediated phosphorylation and inhibition of SLC9A3. May enhance Wnt signaling.

Requested From: United States
Date Requested: 10/21/2016

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