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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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SLC8A3 / NCX3 Antibody (aa27‑40) LS‑C154996
Antibody
NCX3 antibody LS-C154996 is an unconjugated goat polyclonal antibody to mouse NCX3 (SLC8A3). Validated for Peptide-ELISA.
Catalog
Size
Price
LS-C154996-100
100 µg (0.5 mg/ml)
Unavailable

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Product Description

NCX3 antibody LS-C154996 is an unconjugated goat polyclonal antibody to mouse NCX3 (SLC8A3). Validated for Peptide-ELISA.
About SLC8A3 / NCX3
SLC8A3 / NCX3 is a member of the sodium/calcium exchanger integral membrane protein family. Na+/Ca2+ exchange proteins are involved in maintaining Ca2+ homeostasis in a wide variety of cell types. The protein is regulated by intracellular calcium ions and is found in both the plasma membrane and intracellular organellar membranes, where exchange of Na+ for Ca2+ occurs in an electrogenic manner. Alternative splicing has been observed for this gene and multiple variants have been described. P57103 NM_033262 NP_150287.1

SLC8A3 Antibody, Na+/Ca2+ exchanger 3 Antibody, NCX2 Antibody, NCX3 Antibody, Sodium-calcium exchanger 3 Antibody, Sodium/calcium exchanger 3 Antibody


Specifications

Target
Mouse SLC8A3 / NCX3
Host
Goat
Reactivity
Mouse (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • Peptide Enzyme-Linked Immunosorbent Assay (1:64000)
Immunogen
SLC8A3 / NCX3 antibody was raised against synthetic peptide CLRAEAGDSGDVPS from the N-terminus of mouse SLC8A3 (NP_001161392.1; NP_536688.2). Percent identity by BLAST analysis: Mouse (100%); Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey, Galago, Marmoset, Hamster, Bovine, Horse, Rabbit, Porcine (86%).
Blocking Peptide
LS-E27868 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C154996. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Epitope
aa27-40
Specificity
Mouse SLC8A3. This antibody is expected to recognize both reported isoforms (NP_001161392.1; NP_536688.2).
Usage
Peptide ELISA: antibody detection limit dilution 1:64000. Western blot: Preliminary experiments gave an approx 28kD band in Mouse Brain lysates after 1 ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 102kD according to NP_001161392.1. The 28kD band was successfully blocked by incubation with the immunizing peptide.
Presentation
Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
Storage
Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/18/2018

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