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Anti-SLC5A11 / SMIT2 Antibody (Extracellular Domain) IHC-plus™ LS-A2797

Note: This antibody replaces LS-C42475

Ordering

Wt. Vol. Conc. Price
50 µg 50 µl 1 mg/ml $395
Inquire for larger quantities
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Rabbit Polyclonal to Human SLC5A11 / SMIT2
Human, Monkey
IHC - Paraffin
Unconjugated

Details

Human SLC5A11 / SMIT2
Rabbit
Human, Monkey (tested or 100% immunogen sequence identity)
Horse, Pig, Rabbit (at least 90% immunogen sequence identity)
Polyclonal
Immunoaffinity purified

Applications

IHC - Paraffin (10 µg/ml)

Specificity and Use

SLC5A11 / SMIT2 antibody was raised against synthetic 17 amino acid peptide from extracellular domain of human SLC5A11. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset (100%); Rabbit, Horse, Pig (94%); Rat, Elephant (88%); Mouse, Dog, Bovine, Hamster, Opossum, Turkey, Chicken (82%).
LS-E28628 - Liquid - 50 µg - $145.00
Extracellular Domain
Human SLC5A11. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except SLC5A2 (65%), SLC5A9 (65%).
Immunohistochemistry: LS-A2797 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-A2797 was determined to be 10 ug/ml.

Packaging

PBS, less than 0.1% sodium azide.
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze thaw cycles.
For research use only.

About SLC5A11 / SMIT2

Q8WWX8 NM_052944 NP_443176.2

SLC5A11 Antibody, Homolog of rabbit KST1 Antibody, KST1 Antibody, SLGTX Antibody, SMIT2 Antibody, RKST1 Antibody, SGLT6 Antibody

Involved in the sodium-dependent cotransport of myo-inositol (MI) with a Na+:MI stoichiometry of 2:1. Exclusively responsible for apical MI transport and absorption in intestine. Also can transport D-chiro-inositol (DCI) but not L-fructose. Exhibits stereospecific cotransport of both D-glucose and D-xylose. May induce apoptosis through the TNF-alpha, PDCD1 pathway.

Immunohistochemistry

Immunohistochemistry
Anti-SLC5A11 antibody LS-A2797 IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
 

Requested From: United States
Date Requested: 9/30/2016

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