Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Human, Mouse, Rabbit (at least 90% immunogen sequence identity)
Western blot (1 - 10 µg/ml)
ELISA (1:10000 - 1:100000)
SLC4A4 / NBC1 antibody was raised against a 20-aa peptide sequence within the cytoplasmic, N-terminus of rat pNBC1 (1) was used to generate anti-NBC1.
Recognizes rat NBC1. Species sequence homology: mouse, rat, human and rabbit pNBC1/PSLC4A5-100%. This region is unique to the pancreatic isoforms and it is not found in kidney isoform, kNBC/PSLC4A4. No significant sequence homology of was found with NBC2 or NBC3.
Suitable for use in ELISA and Western Blot. ELISA: 1 ul using 50-100 ng of control peptide/well.
PBS, 0.05% Sodium Azide, 40% Glycerol
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Electrogenic sodium/bicarbonate cotransporter with a Na+:HCO3- stoichiometry varying from 1:2 to 1:3. May regulate bicarbonate influx/efflux at the basolateral membrane of cells and regulate intracellular pH.