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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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SLC4A11 / NABC1 Antibody (aa136‑150) IHC‑plus™ LS‑B9208
Note: This antibody replaces LS-C108909
NABC1 antibody LS-B9208 is an unconjugated goat polyclonal antibody to NABC1 (SLC4A11) from human and monkey. Validated for IHC, Peptide-ELISA and WB. Tested on 20 paraffin-embedded human tissues.
Catalog
Size
Price
LS-B9208-50
50 µg (0.5 mg/ml)
Unavailable

Popular SLC4A11 / NABC1 Products

Western blot of extracts from NIH-3T3/RAW264.7/A549 cells, using SLC4A11 Antibody. The lane on the right is treated with the synthesized peptide.
Species: Human
Applications: Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Western blot of the lysates from HT-29 cells using SLC4A11 antibody.
Species: Human
Applications: Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Western blot analysis of NaBC1 expression in MCF7 (A); RAW264.7 (B) whole cell lysates.
Species: Human, Mouse
Applications: Western blot, Immunoprecipitation
Western blot of BTR1 antibody
Species: Human
Applications: Western blot, ELISA

Product Description

NABC1 antibody LS-B9208 is an unconjugated goat polyclonal antibody to NABC1 (SLC4A11) from human and monkey. Validated for IHC, Peptide-ELISA and WB. Tested on 20 paraffin-embedded human tissues.
About SLC4A11 / NABC1
Transporter which plays an important role in sodium-mediated fluid transport in different organs. Prevents severe morphological changes of the cornea caused by increased sodium chloride concentrations in the stroma. In the inner ear, is involved in transport of potassium through the fibrocyte layer to the stria vascularis and is essential for the generation of the endocochlear potential but not for regulation of potassium concentrations in the endolymph. Q8NBS3 NM_032034 NP_114423.1

SLC4A11 Antibody, CDPD1 Antibody, CHED2 Antibody, FECD4 Antibody, DJ794I6.2 Antibody, Sodium borate cotransporter 1 Antibody, BTR1 Antibody, CDPD Antibody, NABC1 Antibody


Specifications

Target
Human SLC4A11 / NABC1
Host
Goat
Reactivity
Human, Monkey (tested or 100% immunogen sequence identity)
Predicted
Mouse, Rat, Bat, Bovine, Hamster, Horse, Rabbit, Chicken, Xenopus (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (3.75 µg/ml)
  • Western blot (0.3 - 1 µg/ml)
  • Peptide Enzyme-Linked Immunosorbent Assay (1:32000)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
SLC4A11 / NABC1 antibody was raised against synthetic peptide C-HTSRKYLKLKNFKEE from an internal region of human SLC4A11 (NP_114423.1). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset (100%); Mouse, Rat, Hamster, Elephant, Bat, Bovine, Horse, Rabbit, Turkey, Chicken, Xenopus (93%); Dog (80%).
Blocking Peptide
LS-E27195 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-B9208. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Epitope
aa136-150
Specificity
Human SLC4A11.
Usage
Western Blot: Approx 90kD band observed in Human, Mouse and Rat Kidney lysates (calculated MW of 99.6kD according to NP_114423.1). Recommended concentration: 0.3-1 ug/ml. An additional band of unknown identity was also consistently observed at 26kD. This band was successfully blocked by incubation with the immunizing peptide.
Presentation
Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
Storage
Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Immunohistochemistry

Anti-SLC4A11 / NABC1 antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-SLC4A11 / NABC1 antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Western blot

SLC4A11 antibody (0.3 ug/ml) staining of Human Kidney lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
SLC4A11 antibody (0.3 ug/ml) staining of Human Kidney lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Immunohistochemistry

Anti-SLC4A11 / NABC1 antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-SLC4A11 / NABC1 antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Western blot

SLC4A11 antibody (0.3 ug/ml) staining of Human Kidney lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
SLC4A11 antibody (0.3 ug/ml) staining of Human Kidney lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Immunohistochemistry

Anti-SLC4A11 / NABC1 antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-SLC4A11 / NABC1 antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Western blot

SLC4A11 antibody (0.3 ug/ml) staining of Human Kidney lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
SLC4A11 antibody (0.3 ug/ml) staining of Human Kidney lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Immunohistochemistry

Anti-SLC4A11 / NABC1 antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-SLC4A11 / NABC1 antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Western blot

SLC4A11 antibody (0.3 ug/ml) staining of Human Kidney lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
SLC4A11 antibody (0.3 ug/ml) staining of Human Kidney lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.


Requested From: 
Date Requested: 6/19/2018

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