Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
(tested or 100% immunogen sequence identity)
Rat (at least 90% immunogen sequence identity)
Western blot (1 - 10 µg/ml)
ELISA (0.5 - 1 µg/ml)
Synthetic peptide consisting of 19aa sequence located within the predicted cytoplasmic C-terminus of mouse MTP1 (KLH coupled).
Recognizes mouse Metal Transporter Protein. Does not distinguish between isoforms ferroprotein1/IREG1, ferroprotein 1 and IRG1/ferroprotein1. Sequence Homology: mouse ferroprotein1/IREG1:100%; rat ferroprotein 1:90%; human and chimp ferroprotein1:78% and rabbit MTP1/IREG1/ferroprotein 1:73%.
Suitable for use in ELISA and Western Blot. ELISA: 0.5-1 ug/ml. Coat with 1 ug/ml Control Peptide. Western Blot: 1-10 ug/ml (ECL).
PBS, pH 7.4, 0.1% BSA
Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles.
May be involved in iron export from duodenal epithelial cell and also in transfer of iron between maternal and fetal circulation. Mediates iron efflux in the presence of a ferroxidase (hephaestin and/or ceruloplasmin).