Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
(tested or 100% immunogen sequence identity)
Rat (at least 90% immunogen sequence identity)
Western blot (1:1000 - 1:5000)
ELISA (1:10000 - 1:50000)
Synthetic 19aa peptide sequence located within the predicted cytoplasmic C-terminus of mouse MTP1 (KLH coupled).
Recognizes mouse Metal Transporter Protein. Does not distinguish between isoforms ferroprotein1/IREG1, ferroprotein 1 and IRG1/ferroprotein1. Species sequence Homology: Mouse ferroprotein1/IREG1:100%; rat ferroprotein 1:90%; human IREG1/ferroprotein1:78%.
Suitable for use in ELISA and Western Blot. Western Blot: 1:1000-1:5000. ELISA: 1:10000-1:50000. Coat with 1 ug/ml Control Peptide.
PBS, 0.05% Sodium Azide
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
May be involved in iron export from duodenal epithelial cell and also in transfer of iron between maternal and fetal circulation. Mediates iron efflux in the presence of a ferroxidase (hephaestin and/or ceruloplasmin).