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Anti-SLC2A4 / GLUT-4 Antibody IHC-plus™ LS-B26

Note: This antibody replaces LS-C11345


Wt. Vol. Conc. Price
- 50 µl 5 mg/ml $395
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)

Most Popular SLC2A4 / GLUT-4 Antibodies

Anti-SLC2A4 / GLUT-4 Antibody IHC-plus™ LS-B26
Rabbit Polyclonal to Human SLC2A4 / GLUT-4
Human, Monkey, Mouse, Rat
IHC - Paraffin, IHC - Frozen, Western blot, Immunoprecipitation
Immunohistochemistry Image
Anti-SLC2A4 / GLUT-4 Antibody (aa36-85) LS-C110819
Rabbit Polyclonal to Human SLC2A4 / GLUT-4
Human, Monkey, Bat, Bovine, Dog, Goat, Guinea pig, Horse, Pig, Rabbit
Western blot
Western blot Image
Anti-SLC2A4 / GLUT-4 Antibody (N-Terminus) LS-C127596
Rabbit Polyclonal to Human SLC2A4 / GLUT-4
IHC, Western blot, ELISA

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal to Human SLC2A4 / GLUT-4
Human, Monkey, Mouse, Rat
IHC - Paraffin, IHC - Frozen, Western blot, Immunoprecipitation


Human SLC2A4 / GLUT-4
Human, Monkey, Mouse, Rat (tested or 100% immunogen sequence identity)
Affinity purified


  • IHC - Paraffin (10 - 20 µg/ml)
  • IHC - Frozen
  • Western blot
  • Immunoprecipitation

Specificity and Use

SLC2A4 / GLUT-4 antibody was raised against a 12 amino acid peptide corresponding to the carboxyl terminus of the insulin regulatable glucose transporter  conjugated to keyhole limpet hemocyanin.
Recognizes human Solute carrier family 2, facilitated glucose transporter member 4, also known as glucose transporter 4 or GLUT4. GLUT4 is a 509 amino acid ~50 kD multi-pass transmembrane protein located primarily in the perinuclear region and is translocated to the plasma membrane where it is rapidly reinternalized. Does not react with HEP G2 type glucose transporter in human erythrocytes, rat brain or other tissues that do not exhibit sensitivity to insulin. GLUT4 is the insulin-regulated glucose transporter found in adipose tissue and striated muscle, responsible for glucose disposal. The stimulation of glucose uptake by insulin requires translocation of the GLUT4 glucose transporter from intracellular storage sites to the cell surface. Activation of phosphatidylinositol-3-OH kinase (PI3K) is required for this trafficking event, but it is not sufficient to produce GLUT4 translocation. Human insulin resistance involves a defect in GLUT4 traffic and targeting leading to accumulation in a dense membrane compartment from which insulin is unable to recruit GLUT4 to the cell surface.
Immunohistochemistry: LS-B26 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B26 was determined to be 10-20 ug/ml.


PBS, 0.09% sodium azide.
+4°C or -20°C, Avoid repeated freezing and thawing.
For research use only.

About SLC2A4 / GLUT-4

P14672 NM_001042 NP_001033.1

SLC2A4 Antibody, Glucose transporter 4 Antibody, Glucose transporter GLUT4 Antibody, GLUT4 Antibody, GLUT-4 Antibody

SLC2A4 / GLUT-4 is a member of the solute carrier family 2 (facilitated glucose transporter) family and encodes a protein that functions as an insulin-regulated facilitative glucose transporter. In the absence of insulin, this integral membrane protein is sequestered within the cells of muscle and adipose tissue. Within minutes of insulin stimulation, the protein moves to the cell surface and begins to transport glucose across the cell membrane.


Anti-SLC2A4 / GLUT4 antibody IHC of human heart, cardiac myocytes. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B26 concentration 20 ug/ml.

Requested From: United States
Date Requested: 10/22/2016

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