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SLC1A2 / EAAT2 / GLT-1
solute carrier family 1 (glial high affinity glutamate transporter), member 2
SLC1A2 / EAAT2 / GLT-1 is a member of a family of solute transporter proteins. The membrane-bound protein is the principal transporter that clears the excitatory neurotransmitter glutamate from the extracellular space at synapses in the central nervous system. Glutamate clearance is necessary for proper synaptic activation and to prevent neuronal damage from excessive activation of glutamate receptors. Mutations in and decreased expression of this protein are associated with amyotrophic lateral sclerosis. Alternatively spliced transcript variants of this gene have been identified.
| Gene Name: | solute carrier family 1 (glial high affinity glutamate transporter), member 2 |
| Family/Subfamily: | Transporter , Sodium:dicarboxylate symporter |
| Synonyms: | SLC1A2, EAAT-2, GLT-1, Glutamate transporter 1, EAAT2, GLT1 |
| Target Sequences: | NM_004171 NP_004162.2 P43004 |
Publications (2)
1
Pharmacological inhibitions of glutamate transporters EAAT1 and EAAT2 compromise glutamate transport in photoreceptor to ON-bipolar cell synapses. Tse DY, Chung I, Wu SM. Vision research. 2014 103:49-62. (IHC; Rat)
[Full Text Article]
[PubMed:25152321]
[PMC:PMC4547049]
Related Antibodies: LS-C15448.
2
Unbiased Proteomic Approach Identifies Pathobiological Profiles in the Brains of Preclinical Models of Repetitive Mild Traumatic Brain Injury, Tauopathy, and Amyloidosis. Joseph O Ojo, Gogce Crynen, Moustafa Algamal, Prashanti Vallabhaneni, Paige Leary, Benoit Mouzon, Jon M Reed, Michael Mullan, Fiona Crawford. ASN neuro. 2020 Jan-Dec;12:1.75909142091476E+15. [Full Text Article]
[PubMed:32241177]
[PMC:PMC7132820]
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Neuroscience
SLC1A2 / EAAT2 / GLT-1 Mouse anti-Human Monoclonal (C-Terminus) Antibody
Mouse, Human
ICC, IHC, IHC-P, WB
Unconjugated
50 µg/$485
SLC1A2 / EAAT2 / GLT-1 Mouse anti-Human Monoclonal (HRP) Antibody
Mouse, Human
ICC, IHC, WB
HRP Conjugated
100 µl/$1,094
SLC1A2 / EAAT2 / GLT-1 Mouse anti-Human Monoclonal (Biotin) Antibody
Mouse, Human
ICC, IHC, WB
Biotin Conjugated
100 µl/$1,094
SLC1A2 / EAAT2 / GLT-1 Mouse anti-Human Monoclonal (APC) Antibody
Mouse, Human
ICC, IHC, WB
APC Conjugated
100 µl/$1,094
SLC1A2 / EAAT2 / GLT-1 Mouse anti-Human Monoclonal (PE) Antibody
Mouse, Human
ICC, IHC, WB
PE Conjugated
100 µl/$1,094
SLC1A2 / EAAT2 / GLT-1 Guinea pig anti-Rat Polyclonal (aa546-565) Antibody
Rabbit, Mouse, Rat, Human, Monkey
IHC
Unconjugated
50 µl/$882
SLC1A2 / EAAT2 / GLT-1 Rabbit anti-Human Polyclonal (aa144-193) Antibody
Rat, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
SLC1A2 / EAAT2 / GLT-1 Rabbit anti-Human Polyclonal (aa144-193) (HRP) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Horse, Human
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
SLC1A2 / EAAT2 / GLT-1 Rabbit anti-Human Polyclonal (aa144-193) (Biotin) Antibody
Rabbit, Mouse, Dog, Guinea pig, Sheep, Bovine, Rat, Horse, Human
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
SLC1A2 / EAAT2 / GLT-1 Rabbit anti-Human Polyclonal (aa144-193) (FITC) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Horse, Human
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
SLC1A2 / EAAT2 / GLT-1 Rabbit anti-Human Polyclonal (aa467-516) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
SLC1A2 / EAAT2 / GLT-1 Rabbit anti-Human Polyclonal (aa467-516) (Biotin) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Horse, Human
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
Sandwich
96-Well Strip Plate
Human
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Tissue Homogenates
1 Plate/$834
Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$854
SLC1A2 / EAAT2 / GLT-1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
Flo, ICC, IHC-P
Unconjugated
100 µl/$447
SLC1A2 / EAAT2 / GLT-1 Mouse anti-Human Monoclonal (1D8) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$423
SLC1A2 / EAAT2 / GLT-1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Rat, Human
IHC, WB
Unconjugated
100 µl/$440; 200 µl/$468
SLC1A2 / EAAT2 / GLT-1 Rabbit anti-Rat Polyclonal (aa500-550) Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
500 µg/$393
Wheat Germ Extract
GST
88.5 kDa
2 µg/$439
SLC1A2 / EAAT2 / GLT-1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
SLC1A2 / EAAT2 / GLT-1 Rabbit anti-Human Polyclonal (aa117-166) Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
SLC1A2 / EAAT2 / GLT-1 Rabbit anti-Human Polyclonal (aa460-574) Antibody
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50 µg/$294; 100 µg/$360
SLC1A2 / EAAT2 / GLT-1 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
50 µl/$286; 100 µl/$321
Neuroscience
SLC1A2 / EAAT2 / GLT-1 Rabbit anti-Human Polyclonal (Cytoplasmic Domain) Antibody
Mouse, Rat, Human
ELISA, IHC-P, IP, WB
Unconjugated
50 µg/$460
SLC1A2 / EAAT2 / GLT-1 Rabbit anti-Human Polyclonal (aa495-574) Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
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