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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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SLC1A1 / EAAT3 Antibody (aa510‑523) LS‑C152890
Note: This antibody replaces LS-C15445
EAAT3 antibody LS-C152890 is an unconjugated mouse monoclonal antibody to EAAT3 (SLC1A1) from mouse and rat. Validated for IHC and WB.
Catalog
Size
Price
LS-C152890-100
100 µg (1 mg/ml)
Unavailable

Popular SLC1A1 / EAAT3 Products

Antibody
Species: Rat, Human, Monkey, Mouse, Guinea pig, Rabbit
Applications: IHC, IHC - 4% paraformaldehyde
Antibody
Species: Human, Mouse, Rat
Applications: IHC, Western blot
Western blot Image
Species: Human
Applications: Western blot, ELISA
Immunohistochemistry Image
Species: Human
Applications: IHC, IHC - Paraffin, Western blot
Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
Species: Human, Mouse, Rat
Applications: IHC, IHC - Paraffin, Immunofluorescence, Western blot

Product Description

EAAT3 antibody LS-C152890 is an unconjugated mouse monoclonal antibody to EAAT3 (SLC1A1) from mouse and rat. Validated for IHC and WB.
About SLC1A1 / EAAT3
SLC1A1 / EAAT3 is a member of the high-affinity glutamate transporters that play an essential role in transporting glutamate across plasma membranes. In brain, these transporters are crucial in terminating the postsynaptic action of the neurotransmitter glutamate, and in maintaining extracellular glutamate concentrations below neurotoxic levels. P43005 NM_004170 NP_004161.4

SLC1A1 Antibody, EAAC1 Antibody, EAAT3 Antibody, Eaac-1 Antibody


Specifications

Target
Rat SLC1A1 / EAAT3
Host
Mouse
Reactivity
Rat, Mouse (tested or 100% immunogen sequence identity)
Predicted
Human, Monkey, Bovine, Dog, Guinea pig, Hamster, Horse, Rabbit, Chicken (at least 90% immunogen sequence identity)
Clonality
IgG1 Monoclonal
Conjugations
Unconjugated
Purification
Purified
Modifications
Unmodified
Applications
  • IHC
  • Western blot (1 - 2 µg/ml)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
SLC1A1 / EAAT3 antibody was raised against c-terminus peptide (KDKSDTISFTQTSQF) Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Monkey, Galago, Marmoset, Mouse, Rat, Dog, Bovine, Hamster, Panda, Horse, Rabbit, Opossum, Guinea pig, Turkey, Zebra finch, Chicken, Lizard (93%); Elephant, Pig, Platypus, Xenopus (87%); Bat, Pufferfish, Zebrafish (80%).
Epitope
aa510-523
Specificity
Glutamate Transporter EAAC1. Based on protein sequence the antibody is expected to react with mouse, bovine and rabbit
Usage
Western blot: 1-2 ug/ml. Immunohistochemistry: 1-2 ug/ml. Optimal working dilutions must be determined by end user. EAAC1 is approximately 66-70kD; the protein can form homomultimers during preparation as well, thus often times large 200-220kD bands can a
Presentation
0.02 M phosphate buffer, pH 7.6, 0.25 M sodium chloride, 0.1% sodium azide
Storage
Store at 4°C.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Immunohistochemistry

IHC: Mouse anti-Glutamate Transporter [EAAC1] (LS-C152890) staining of rat cerebral cortex.
IHC: Mouse anti-Glutamate Transporter [EAAC1] (LS-C152890) staining of rat cerebral cortex.

Immunohistochemistry

IHC: Mouse anti-Glutamate Transporter [EAAC1] (LS-C152890) staining of rat cerebral cortex.
IHC: Mouse anti-Glutamate Transporter [EAAC1] (LS-C152890) staining of rat cerebral cortex.

Immunohistochemistry

IHC: Mouse anti-Glutamate Transporter [EAAC1] (LS-C152890) staining of rat cerebral cortex.
IHC: Mouse anti-Glutamate Transporter [EAAC1] (LS-C152890) staining of rat cerebral cortex.

Immunohistochemistry

IHC: Mouse anti-Glutamate Transporter [EAAC1] (LS-C152890) staining of rat cerebral cortex.
IHC: Mouse anti-Glutamate Transporter [EAAC1] (LS-C152890) staining of rat cerebral cortex.


Requested From: 
Date Requested: 6/18/2018

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