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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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SLC12A7 / KCC4 Antibody (N‑Terminus) LS‑C16129
KCC4 antibody LS-C16129 is an unconjugated rabbit polyclonal antibody to mouse KCC4 (SLC12A7). Validated for ELISA and WB.
Antibody
Catalog
Size
Price
LS-C16129-100
100 µg
$755

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Product Description

KCC4 antibody LS-C16129 is an unconjugated rabbit polyclonal antibody to mouse KCC4 (SLC12A7). Validated for ELISA and WB.

Specifications

Target
Mouse SLC12A7 / KCC4
Synonyms
SLC12A7, DKFZP434F076, K-Cl cotransporter 4, KCC4
Host
Rabbit
Reactivity
Mouse (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • Western blot (1 - 10 µg/ml)
  • ELISA (1:10000 - 1:100000)
Immunogen
SLC12A7 / KCC4 antibody was raised against a 16aa peptide sequence within the cytoplasmic, N-terminus of mouse KCC4 (KLH coupled).
Epitope
N-Terminus
Specificity
Recognizes KCC4 (K, Cl Cotransporter 4). Species sequence Homology: human: 81%. No significant sequence homology with other KCCs or CCC.
Usage
Suitable for use in ELISA and Western Blot. Western Blot: 1-10 ug/ml using Chemiluminescence technique. ELISA: 1:10000-1:100000. Use 50-100 ng of control peptide/well.
Presentation
100 mM Tris, pH 7.5, 0.02% BSA, 0.05% sodium azide, 40% glycerol.
Storage
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
About SLC12A7 / KCC4
Mediates electroneutral potassium-chloride cotransport when activated by cell swelling. May mediate K+ uptake into Deiters' cells in the cochlea and contribute to K+ recycling in the inner ear. Important for the survival of cochlear outer and inner hair cells and the maintenance of the organ of Corti. May be required for basolateral Cl- extrusion in the kidney and contribute to renal acidification. Q9Y666 NM_006598 NP_006589.2


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Requested From: United States
Date Requested: 10/21/2018

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