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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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SLC12A5 / KCC2 Antibody (N‑Terminus) LS‑C24943 Best Seller
Antibody
KCC2 antibody LS-C24943 is an unconjugated rabbit polyclonal antibody to KCC2 (SLC12A5) from mouse and rat. Validated for ELISA and WB.
Catalog
Size
Price
LS-C24943-50
50 µg (1 mg/ml)
Unavailable

Popular SLC12A5 / KCC2 Products

SLC12A5 / KCC2 antibody LS-C110846 Western blot of Fetal Spleen lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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SLC12A5 / KCC2 antibody LS-C135150 Western blot of Mouse Brain lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Antibody
Species: Human, Mouse, Rat
Applications: IHC, Western blot, Immunoprecipitation
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Species: Rat, Human, Mouse
Applications: IHC, Western blot, Immunoprecipitation

Product Description

KCC2 antibody LS-C24943 is an unconjugated rabbit polyclonal antibody to KCC2 (SLC12A5) from mouse and rat. Validated for ELISA and WB.
About SLC12A5 / KCC2
K-Cl cotransporters are proteins that lower intracellular chloride concentrations below the electrochemical equilibrium potential. The protein encoded by this gene is an integral membrane K-Cl cotransporter that can function in either a net efflux or influx pathway, depending on the chemical concentration gradients of potassium and chloride. The encoded protein can act as a homomultimer, or as a heteromultimer with other K-Cl cotransporters, to maintain chloride homeostasis in neurons. Q9H2X9 NM_020708 NP_065759.1

SLC12A5 Antibody, Erythroid K-Cl cotransporter 2 Antibody, HKCC2 Antibody, K-Cl cotransporter 2 Antibody, KCC2 Antibody, KIAA1176 Antibody, Neuronal K-Cl cotransporter Antibody


Specifications

Target
Rat SLC12A5 / KCC2
Host
Rabbit
Reactivity
Rat, Mouse (tested or 100% immunogen sequence identity)
Predicted
Human (at least 90% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • Western blot (1 - 10 µg/ml)
  • ELISA (1:10000 - 1:100000)
Immunogen
SLC12A5 / KCC2 antibody was raised against an 18aa peptide sequence within the cytoplasmic, N-terminus of rat KCC2 was used to generate anti-KCC2.
Epitope
N-Terminus
Specificity
Recognizes rat KCC2. No significant sequence homology is seen with other KCCs or CCC. Species sequence Homology: Human and mouse - 94%.
Usage
Suitable for use in Western Blot and ELISA. Western Blot: 1-10 ug/ml using Chemiluminescence technique. ELISA: 1:10000-1:100000 using 50-100 ng of control peptide/well.
Presentation
100 mM Tris, pH 7.5, 0.2% BSA, 0.05% sodium azide, 40% glycerol.
Storage
4°C or -20°C, Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/20/2018

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