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Mediates electroneutral potassium-chloride cotransport when activated by cell swelling. May contribute to cell volume homeostasis in single cells. May be involved in the regulation of basolateral Cl- exit in NaCl absorbing epithelia (By similarity). Isoform 4 has no transport activity.
Gene Name: | solute carrier family 12 (potassium/chloride transporter), member 4 |
Family/Subfamily: | Transporter , Cation:chloride symporter |
Synonyms: | SLC12A4, Erythroid K-Cl cotransporter 1, HKCC1, KCC1, K-Cl cotransporter, Erythroid K:Cl cotransporter |
Target Sequences: | NM_005072 NP_005063.1 Q9UP95 |
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