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Anti-SLC12A4 / KCC1 Antibody (aa997-1007) IHC-plus™ LS-B2377

Note: This antibody replaces LS-C55024
Catalog Size Price
LS-B2377-50 50 µg (0.5 mg/ml) Unavailable

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Anti-SLC12A4 / KCC1 Antibody (aa997-1007) IHC-plus™ LS-B2377
Goat Polyclonal to Human SLC12A4 / KCC1
Human, Mouse, Rat, Bat, Dog, Hamster
IHC - Paraffin, Western blot, ELISA
Immunohistochemistry Image
Anti-SLC12A4 / KCC1 Antibody (clone 1H6) LS-C198216
Mouse Monoclonal [clone 1H6] (IgG1,k) to Human SLC12A4 / KCC1
Western blot, ELISA
Western blot Image
Anti-SLC12A4 / KCC1 Antibody LS-C398010
Rabbit Polyclonal (IgG) to Human SLC12A4 / KCC1
IHC - Paraffin, ELISA
Immunohistochemistry Image
Anti-SLC12A4 / KCC1 Antibody LS-C401030
Rabbit Polyclonal (IgG) to Human SLC12A4 / KCC1
Human, Mouse, Rat
Immunohistochemistry Image
Anti-SLC12A4 / KCC1 Antibody LS-C404286
Rabbit Polyclonal (IgG) to Human SLC12A4 / KCC1
Human, Mouse, Rat
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100% Guaranteed Publications (1)
Goat Polyclonal to Human SLC12A4 / KCC1
Human, Mouse, Rat, Bat, Dog, Hamster
IHC - Paraffin, Western blot, ELISA


Human SLC12A4 / KCC1
Human, Mouse, Rat, Bat, Dog, Hamster (tested or 100% immunogen sequence identity)
Monkey, Bovine, Horse, Rabbit (at least 90% immunogen sequence identity)
Immunoaffinity purified


  • IHC - Paraffin (5 µg/ml)
  • Western blot (0.3 - 1 µg/ml)
  • ELISA (1:4000)

Specificity and Use

SLC12A4 / KCC1 antibody was raised against synthetic peptide C-DPSHAPDNFRE from an internal region of human SLC12A4 (NP_005063.1). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Mouse, Rat, Hamster, Elephant, Dog, Bat (100%); Marmoset, Panda, Bovine, Rabbit, Horse (91%).
LS-E26489 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-B2377. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Human SLC12A4.
Immunohistochemistry: LS-B2377 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B2377 was determined to be 5 ug/ml.


Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
Store at -20°C. Avoid freeze-thaw cycles.
For research use only.

Publications (1)

The Zn(2+)-sensing receptor, ZnR/GPR39, upregulates colonocytic Cl(-) absorption, via basolateral KCC1, and reduces fluid loss. Sunuwar L, Asraf H, Donowitz M, Sekler I, Hershfinkel M. Biochimica et biophysica acta. 2017 1863:947-960. (WB; Human) [Full Text Article] [PubMed:28093242] [PMC:PMC5557417]

About SLC12A4 / KCC1

Q9UP95 NM_005072 NP_005063.1

SLC12A4 Antibody, Erythroid K-Cl cotransporter 1 Antibody, HKCC1 Antibody, KCC1 Antibody, K-Cl cotransporter Antibody, Erythroid K:Cl cotransporter Antibody

Mediates electroneutral potassium-chloride cotransport when activated by cell swelling. May contribute to cell volume homeostasis in single cells. May be involved in the regulation of basolateral Cl- exit in NaCl absorbing epithelia (By similarity). Isoform 4 has no transport activity.


Anti-SLC12A4 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2377 concentration 5 ug/ml.

Western blot

Western blot
Antibody (0.3 ug/ml) staining of Human Heart lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Requested From: 
Date Requested: 3/24/2018

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