Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
HIV modulates the expression of ligands important in triggering natural killer cell cytotoxic responses on infected primary T-cell blasts. Ward J, Bonaparte M, Sacks J, Guterman J, Fogli M, Mavilio D, Barker E. Blood. 2007 110:1207-14.
Trogocytosis is a gateway to characterize functional diversity in melanoma-specific CD8+ T cell clones. Uzana R, Eisenberg G, Sagi Y, Frankenburg S, Merims S, Amariglio N, Yefenof E, Peretz T, Machlenkin A, Lotem M. Journal of immunology (Baltimore, Md. : 1950). 2012 188:632-40.
SLAMF6 Antibody, Activating NK receptor Antibody, CD352 Antibody, CD352 antigen Antibody, NK-T-B-antigen Antibody, NTB-A Antibody, NTBA receptor Antibody, KALIb Antibody, SF2000 Antibody, SLAM family member 6 Antibody, Ly108 Antibody, NTBA Antibody, KALI Antibody
SLAMF6 / NTBA is a type I transmembrane protein, belonging to the CD2 subfamily of the immunoglobulin superfamily. This encoded protein is expressed on Natural killer (NK), T, and B lymphocytes. It undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs). It functions as a coreceptor in the process of NK cell activation.