Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone JM1E3] (IgG1) to Pig SLA Class I
Immunoprecipitation, Flow Cytometry (applications tested for the base form of this product only)
Pig SLA Class I
Pig, Human (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [JM1E3]
Also available conjugated with FITC.
Protein G purified
(applications tested for the base form of this product only)
Specificity and Use
SLA Class I antibody was raised against porcine peripheral blood mononuclear cells.
The major histocompatibility complex (MHC) is a cluster of genes that are important in the immune response to infections. In pigs, this is referred to as the swine leukocyte antigen (SLA) region. Clone JM1E3 recognizes a monomorphic epitope expressed by porcine MHC class I molecules (SLA - 1). SLA - 1 is expressed by all nucleated porcine cells, but not on erythrocytes. Has also been shown to cross-react with human MHC Class I, including HLA-E. Is reported to block the interaction of MHC Class I antigens with inhibitory NK cell receptors. Removal of sodium azide is recommended prior to use in functional assays -.
PBS, 0.09% sodium azide
+4°C or -20°C, Avoid repeated freezing and thawing.