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Anti-SKP1 Antibody LS-C155251

Catalog	Size	Price
LS-C155251-100	100 µl (1 mg/ml)	Unavailable

Related Products

39 SKP1 Antibodies

Most Popular SKP1 Antibodies

Anti-SKP1 Antibody LS-C37973

Antibody:	Mouse Monoclonal (IgG1) to Human SKP1
Reactivity:	Human
Application:	Western blot, Immunoprecipitation, ELISA
Format:	Unconjugated

Anti-SKP1 Antibody LS-C155330

Antibody:	Rabbit Polyclonal (IgG) to Human SKP1
Reactivity:	Human
Application:	Western blot
Format:	Unconjugated

Sample (30 ug of whole cell lysate) A: 293T 12% SDS PAGE SKP1 antibody diluted at 1:1000

Anti-SKP1 Antibody (clone 4E+11) LS-C169443

Antibody:	Mouse Monoclonal [clone 4E+11] (IgG1) to Human SKP1
Reactivity:	Human
Application:	IHC, IHC - Paraffin, Immunofluorescence, Western blot, Flow Cytometry, ELISA
Format:	Unconjugated

IHC of paraffin-embedded rectum cancer tissues using SKP1 mouse monoclonal antibody with DAB staining.

Anti-SKP1 Antibody (aa58-87, APC) LS-C245878

Antibody:	Rabbit Polyclonal (IgG) to Human SKP1
Reactivity:	Human
Application:	Western blot, ELISA
Format:	APC Conjugated

Anti-SKP1 Antibody (aa2-163, HRP) LS-C370347

Antibody:	Rabbit Polyclonal (IgG) to Human SKP1
Reactivity:	Human
Application:	ELISA
Format:	HRP Conjugated

Antibody:	Rabbit Polyclonal (IgG) to Human SKP1
Reactivity:	Human, Monkey, Rat, Bovine, Chicken, Xenopus
Application:	IHC, IHC - Paraffin, Western blot
Format:	Unconjugated

IHC of paraffin-embedded CL1-5 xenograft, using SKP1 antibody at 1:500 dilution.

Sample (30 ug of whole cell lysate) A: NIH-3T3 12% SDS PAGE SKP1 antibody diluted at 1:3000

Sample (30 ug of whole cell lysate) A: A549 B: H1299 C: HCT116 D: MCF-7 12% SDS PAGE SKP1 antibody diluted at 1:1000

Details

Target:	Human SKP1
Host:	Rabbit
Reactivity:	Human, Monkey, Rat, Bovine, Chicken, Xenopus (tested or 100% immunogen sequence identity)
Predicted:	Zebrafish (at least 90% immunogen sequence identity)
Clonality:	IgG Polyclonal
Conjugations:	Unconjugated
Purification:	Immunoaffinity purified
Modifications:	Unmodified

Applications

Approved:

IHC
IHC - Paraffin (1:100 - 1:1000)
Western blot (1:500 - 1:3000)

Specificity and Use

Immunogen:	SKP1 antibody was raised against recombinant fragment corresponding to a region within amino acids 1 and 163 of SKP1 (SwissProt P63208). Percent identity by BLAST analysis: Human, Chicken, Monkey, Rat, Xenopus, Bovine (100%); Zebrafish (99%).
Specificity:	Human SKP1
Usage:	Suggested starting dilutions are as follows: Western blot: 1:500-1:3000, IHC-Paraffin: 1:100-1:1000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.

Packaging

Presentation:	PBS, pH 7, 1% BSA, 20% Glycerol, 0.01% Thimerosal
Storage:	Aliquot and freeze at -20°C. Avoid freeze-thaw cycles.
Restrictions:	For research use only.

About SKP1

Uniprot: P63208 NCBI: NM_006930 NP_008861.2

Synonyms: SKP1 Antibody, Cyclin A/CDK2-associated p19 Antibody, OCP-2 Antibody, OCP-II Antibody, Organ of Corti protein 2 Antibody, SIII Antibody, TCEB1L Antibody, Organ of Corti protein II Antibody, p19A Antibody, SKP1A Antibody, EMC19 Antibody, OCP2 Antibody, p19skp1 Antibody

Description: Essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as an adapter that links the F-box protein to CUL1. The functional specificity of the SCF complex depends on the F-box protein as substrate recognition component. SCF(BTRC) and SCF(FBXW11) direct ubiquitination of CTNNB1 and participate in Wnt signaling.

(More About SKP1)