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Anti-SKIL / SNO / SnoN Antibody (N-Terminus) IHC-plus™ LS-B553

Note: This antibody replaces LS-C19443

Ordering

Wt. Vol. Conc. Price
50 µg - 0.5 mg/ml $395
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
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Most Popular SKIL / SNO / SnoN Antibodies

Anti-SKIL / SNO / SnoN Antibody (N-Terminus) IHC-plus™ LS-B553
Rabbit Polyclonal to Human SKIL / SNO / SnoN
Human, Mouse, Rat
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image
Anti-SKIL / SNO / SnoN Antibody (aa600-684) IHC-plus™ LS-B2062
Rabbit Polyclonal (IgG) to Human SKIL / SNO / SnoN
Human, Mouse, Rat
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal to Human SKIL / SNO / SnoN
Human, Mouse, Rat
IHC - Paraffin, Western blot
Unconjugated

Details

Human SKIL / SNO / SnoN
Rabbit
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
Polyclonal
Unconjugated
Affinity purified
Unmodified

Applications

  • IHC - Paraffin (2.5 µg/ml)
  • Western blot

Specificity and Use

SKIL / SNO / SnoN antibody was raised against synthetic peptide from human SKIL.
LS-E29929 - Liquid - 50 µg - $145.00
N-Terminus
16 amino acid peptide from near the amino terminus of human SnoN
Immunohistochemistry: LS-B553 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B553 was determined to be 2.5 ug/ml.

Packaging

PBS, 0.02% sodium azide.
Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.
For research use only.

About SKIL / SNO / SnoN

P12757 NM_005414 NP_005405.2

SKIL Antibody, Ski-related oncogene Antibody, SnoI Antibody, SnoN Antibody, SKI-like oncogene Antibody, Sno Antibody, Ski-related oncogene snoN Antibody, Ski-related protein Antibody, Ski-like protein Antibody, SnoA Antibody

SKIL / SNO / SnoN is a component of the SMAD pathway, which regulates cell growth and differentiation through transforming growth factor-beta (TGFB). In the absence of ligand, the encoded protein binds to the promoter region of TGFB-responsive genes and recruits a nuclear repressor complex. TGFB signaling causes SMAD3 to enter the nucleus and degrade this protein, allowing these genes to be activated. Four transcript variants encoding three different isoforms have been found for this gene.

Immunohistochemistry

Immunohistochemistry
Anti-SKIL antibody IHC of human lung, respiratory epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B553 concentration 5 ug/ml.

Immunohistochemistry

Immunohistochemistry
Anti-SKIL antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B553 concentration 5 ug/ml.

Immunofluorescence

Immunofluorescence
Immunofluorescence of SnoN in Mouse Lung cells with SnoN antibody at 20 ug/ml.

Western blot

Western blot
Western blot of SnoN in A431 cell lysate with SnoN antibody at (A) 0.5 and (B) 1 ug/ml.

Requested From: United States
Date Requested: 12/3/2016

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