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Anti-SKIL / SNO / SnoN Antibody (clone 1C12) LS-C198202

Ordering

Wt. Vol. Conc. Price
100 µg - - $355
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular SKIL / SNO / SnoN Antibodies

Anti-SKIL / SNO / SnoN Antibody (N-Terminus) IHC-plus™ LS-B553
Rabbit Polyclonal to Human SKIL / SNO / SnoN
Human, Mouse, Rat
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image
Anti-SKIL / SNO / SnoN Antibody (aa600-684) IHC-plus™ LS-B2062
Rabbit Polyclonal (IgG) to Human SKIL / SNO / SnoN
Human, Mouse, Rat
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Mouse Monoclonal [clone 1C12] (IgG2a,k) to Human SKIL / SNO / SnoN
Human
Western blot, ELISA
Unconjugated

Details

Human SKIL / SNO / SnoN
Mouse
Human (tested or 100% immunogen sequence identity)
IgG2a,k Monoclonal [1C12]
Unconjugated
Protein A purified
Unmodified

Applications

  • Western blot
  • ELISA

Specificity and Use

SKIL / SNO / SnoN antibody was raised against sKIL (NP_005405.1, aa236-313 partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Human SKIL / SNO / SnoN
Sandwich ELISA: Recombinant protein. Western Blot: Transfected lysate, Recombinant protein.

Packaging

PBS, pH 7.2
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
For research use only.

About SKIL / SNO / SnoN

P12757 NM_005414 NP_005405.2

SKIL Antibody, Ski-related oncogene Antibody, SnoI Antibody, SnoN Antibody, SKI-like oncogene Antibody, Sno Antibody, Ski-related oncogene snoN Antibody, Ski-related protein Antibody, Ski-like protein Antibody, SnoA Antibody

SKIL / SNO / SnoN is a component of the SMAD pathway, which regulates cell growth and differentiation through transforming growth factor-beta (TGFB). In the absence of ligand, the encoded protein binds to the promoter region of TGFB-responsive genes and recruits a nuclear repressor complex. TGFB signaling causes SMAD3 to enter the nucleus and degrade this protein, allowing these genes to be activated. Four transcript variants encoding three different isoforms have been found for this gene.

Western blot

Western blot
Western Blot analysis of SKIL expression in transfected 293T cell line by SKIL monoclonal antibody (M01), clone 1C12.Lane 1: SKIL transfected lysate (Predicted MW: 77 KDa).Lane 2: Non-transfected lysate.

Enzyme-Linked Immunosorbent Assay

Enzyme-Linked Immunosorbent Assay
Detection limit for recombinant GST tagged SKIL is 0.03 ng/ml as a capture antibody.

Requested From: United States
Date Requested: 12/7/2016

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