Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
SKAP2 / SCAP2 shares homology with Src kinase-associated phosphoprotein 1, and is a substrate of Src family kinases. It is an adaptor protein that is thought to play an essential role in the Src signaling pathway, and in regulating proper activation of the immune system. This protein contains an amino terminal coiled-coil domain for self-dimerization, a plecskstrin homology (PH) domain required for interactions with lipids at the membrane, and a Src homology (SH3) domain at the carboxy terminus.
IHC of paraffin-embedded lung ca using SCAP2 antibody at 1:100 dilution.
SCAP2 antibody [C2C3], C-term detects SKAP2 protein at cytoplasm by immunofluorescent analysis. HepG2 cells were fixed in 4% paraformaldehyde at RT for 15 min. SKAP2 protein stained by SCAP2 antibody [C2C3], C-term diluted at 1:500.
Sample (30 ug of whole cell lysate). A: Hep G2 . 10% SDS PAGE. SCAP2 antibody. SKAP2 / SCAP2 antibody diluted at 1:1000.