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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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SIX4 Antibody (aa224‑273) LS‑C201255
SIX4 antibody LS-C201255 is an unconjugated rabbit polyclonal antibody to SIX4 from human, mouse, rat and other species. Validated for WB.
Catalog
Size
Price
LS-C201255-50
50 µg (1 mg/ml)
Unavailable

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Product Description

SIX4 antibody LS-C201255 is an unconjugated rabbit polyclonal antibody to SIX4 from human, mouse, rat and other species. Validated for WB.
About SIX4
Transcriptional regulator which can act as both a transcriptional repressor and activator by binding a DNA sequence on these target genes and is involved in processes like cell differentiation, cell migration and cell survival. Transactivates gene expression by binding a 5'-[CAT]A[CT][CT][CTG]GA[GAT]-3' motif present in the Trex site and a 5'-TCA[AG][AG]TTNC-3' motif present in the MEF3 site of the muscle-specific genes enhancer. Q9UIU6 NM_017420 NP_059116.3

SIX4 Antibody, AREC3 Antibody, Homeobox protein SIX4 Antibody, Sine oculis homeobox homolog 4 Antibody, SIX homeobox 4 Antibody


Specifications

Target
Human SIX4
Host
Rabbit
Reactivity
Human, Monkey, Mouse, Rat, Dog, Guinea pig, Horse (tested or 100% immunogen sequence identity)
Predicted
Zebrafish (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated. Also available conjugated with Biotin, FITC, HRP.
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • Western blot (1 µg/ml)
  • (applications tested for the base form of this product only)
Immunogen
SIX4 antibody was raised against synthetic peptide located between aa224-273 of human SIX4 (G3V2N2). Percent identity by BLAST analysis: Human, Chimpanzee, Orangutan, Gibbon, Monkey, Galago, Marmoset, Mouse, Rat, Elephant, Panda, Dog, Horse, Pig, Opossum, Guinea pig (100%); Zebrafish (92%); Xenopus, Medaka (85%).
Epitope
aa224-273
Specificity
Human SIX4
Presentation
Lyophilized from PBS, 2% sucrose.
Reconstitution
50 µl Distilled water
Storage
Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year); Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Western blot

Western blot of Human Pancreas Tumor. SIX4 antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot of Human Pancreas Tumor. SIX4 antibody dilution 1.0 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Western blot of Human Pancreas Tumor. SIX4 antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot of Human Pancreas Tumor. SIX4 antibody dilution 1.0 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Western blot of Human Pancreas Tumor. SIX4 antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot of Human Pancreas Tumor. SIX4 antibody dilution 1.0 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Western blot of Human Pancreas Tumor. SIX4 antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot of Human Pancreas Tumor. SIX4 antibody dilution 1.0 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.


Requested From: 
Date Requested: 6/20/2018

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