SIX1

SIX homeobox 1

Transcription factor that is involved in the regulation of cell proliferation, apoptosis and embryonic development. Plays an important role in the development of several organs, including kidney, muscle and inner ear. Depending on context, functions as transcriptional repressor or activator. Lacks an activation domain, and requires interaction with EYA family members for transcription activation. Mediates nuclear translocation of EYA1 and EYA2. Binds the 5'-TCA[AG][AG]TTNC-3' motif present in the MEF3 element in the MYOG promoter. Regulates the expression of numerous genes, including MYC, CCND1 and EZR. Acts as activator of the IGFBP5 promoter, probably coactivated by EYA2. Repression of precursor cell proliferation in myoblasts is switched to activation through recruitment of EYA3 to the SIX1-DACH1 complex. During myogenesis, seems to act together with EYA2 and DACH2 (By similarity). Regulates the expression of CCNA1.

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Products

Antibodies (27)

Proteins (5)

Type

Over-Expression Lysate (2)

Primary (27)

Recombinant (3)

Target

SIX1 (32)

Reactivity

Human (26)

Mouse (13)

Rat (7)

Bat (3)

Bovine (3)

Chimpanzee (6)

Dog (3)

Gibbon (3)

Guinea pig (3)

Hamster (3)

Horse (3)

Monkey (4)

Pig (6)

Sheep (3)

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Application

IHC (3)

WB (22)

Compet (1)

ELISA (9)

ICC (1)

IF (2)

IP (2)

Peptide-ELISA (3)

Host

rabbit (24)

mouse (3)

Isotype

IgG (16)

IgG1 (2)

IgG2a,k (1)

Clonality

monoclonal mc (3)

polyclonal pc (24)

Clone

3C7 (1)

OTI1H4 (2)

Format

Biotin Conjugated (3)

Carrier-free (1)

FITC Conjugated (3)

HRP Conjugated (3)

Unconjugated (18)

Epitope

C-Terminus (8)

80-160 aa, Internal (1)

aa1-284 (1)

aa111-160 (1)

aa245-282 (1)

aa69-102 (1)

Publications

No (31)

Yes (1)

Tag

GST (1)

His (1)

His, N-Terminal (1)

Myc-DDK (Flag) (2)

Species

Human (4)

Source

293T Cells (1)

E. coli (2)

HEK 293 Cells (1)

Wheat Germ Extract (1)

Purification

Purified (2)

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SIX1 Antibody LS-C490560

(4.0) Rating

(1) Publication(s)

Antibody:

SIX1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µg/$575

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SIX1 Antibody LS-C139037

Antibody:

SIX1 Rabbit anti-Mouse Polyclonal Antibody

Reactivity:

Mouse

Applications:

Compet, ELISA, ICC, IHC, IP, WB

Format:

Unconjugated

Price:

100 µl/$424

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SIX1 Antibody LS-C752531

Antibody:

SIX1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, IP, WB

Format:

Unconjugated

Price:

100 µg/$341

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SIX1 Antibody LS-C500844

Antibody:

SIX1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Rat, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

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SIX1 Antibody (HRP) LS-C500849

Antibody:

SIX1 Rabbit anti-Human Polyclonal (HRP) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

HRP Conjugated

Price:

50 µg/$294; 100 µg/$360

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SIX1 Antibody (Biotin) LS-C500847

Antibody:

SIX1 Rabbit anti-Human Polyclonal (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Biotin Conjugated

Price:

50 µg/$294; 100 µg/$360

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SIX1 Antibody (FITC) LS-C500851

Antibody:

SIX1 Rabbit anti-Human Polyclonal (FITC) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

FITC Conjugated

Price:

50 µg/$294; 100 µg/$360

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

SIX1 Antibody LS-C805122

Antibody:

SIX1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IF, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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SIX1 Antibody (80-160 aa, Internal) LS-C386067

Antibody:

SIX1 Rabbit anti-Human Polyclonal (80-160 aa, Internal) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

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SIX1 Antibody LS-C824201

Antibody:

SIX1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$357

Select

SIX1 Antibody (aa111-160) LS-C291338

Antibody:

SIX1 Rabbit anti-Human Polyclonal (aa111-160) Antibody

Reactivity:

Mouse, Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

Select

SIX1 Antibody (aa69-102) LS-C392817

Antibody:

SIX1 Rabbit anti-Human Polyclonal (aa69-102) Antibody

Reactivity:

Mouse, Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

200 µl/$393

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SIX1 Antibody LS-C831445

Antibody:

SIX1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC

Format:

Unconjugated

Price:

20 µl/$250; 60 µl/$286; 120 µl/$349; 200 µl/$439

Select

SIX1 Antibody (clone 3C7) LS-C198200

Antibody:

SIX1 Mouse anti-Human Monoclonal (3C7) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Unconjugated

Price:

100 µg/$423

Select

SIX1 Antibody (clone OTI1H4) LS-C173609

Antibody:

SIX1 Mouse anti-Human Monoclonal (OTI1H4) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$434

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SIX1 Antibody (aa1-284, clone OTI1H4, Carrier-free) LS-C786728

Antibody:

SIX1 Mouse anti-Human Monoclonal (aa1-284) (Carrier-free) (OTI1H4) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

Select

SIX1 Antibody (C-Terminus) LS-C101389

Antibody:

SIX1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

Select

SIX1 Antibody (C-Terminus, Biotin) LS-C427777

Antibody:

SIX1 Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody

Reactivity:

Mouse, Dog, Guinea pig, Sheep, Bovine, Pig, Horse, Bat, Rat, Hamster, Chimpanzee, Gibbon, Human, Monkey

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

• Unconjugated
• Biotin

• Unconjugated
• Biotin

Select

SIX1 Antibody (C-Terminus) LS-C110311

Antibody:

SIX1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

Select

SIX1 Antibody (C-Terminus, HRP) LS-C437424

Antibody:

SIX1 Rabbit anti-Human Polyclonal (C-Terminus) (HRP) Antibody

Reactivity:

Pig, Human, Chimpanzee

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

Select

SIX1 Antibody (C-Terminus, Biotin) LS-C437422

Antibody:

SIX1 Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody

Reactivity:

Pig, Human, Chimpanzee

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

Select

SIX1 Antibody (C-Terminus, FITC) LS-C437423

Antibody:

SIX1 Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody

Reactivity:

Pig, Human, Chimpanzee

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

SIX1 Antibody LS-C747197

Antibody:

SIX1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

Select

SIX1 Antibody LS-C760967

Antibody:

SIX1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human, Monkey

Applications:

WB

Format:

Unconjugated

Price:

30 µl/$255; 100 µl/$299; 200 µl/$351

Select

SIX1 Antibody (aa245-282) LS-C408101

Antibody:

SIX1 Rabbit anti-Human Polyclonal (aa245-282) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

10 µg/$318; 100 µg/$470

Viewing 1-25 of 32 product results

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