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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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SIT1 Antibody (Intracellular, clone SIT‑01, PE) LS‑C46498
Antibody
SIT1 antibody LS-C46498 is a PE-conjugated mouse monoclonal antibody to human SIT1. Validated for Flow.
Catalog
Size
Price
LS-C46498-100
100 µg (0.1 mg/ml)
Unavailable

Popular SIT1 Products

Antibody
Species: Human
Applications: Western blot, Immunoprecipitation, Flow Cytometry
Antibody
Species: Human
Applications: IHC, Western blot, Immunoprecipitation, Flow Cytometry
Antibody
Species: Human
Applications: Western blot, Immunoprecipitation
Antibody
Species: Human
Applications: Western blot, ELISA

Product Description

SIT1 antibody LS-C46498 is a PE-conjugated mouse monoclonal antibody to human SIT1. Validated for Flow.
About SIT1
Negatively regulates TCR (T-cell antigen receptor)-mediated signaling in T-cells. Involved in positive selection of T-cells. Q9Y3P8 NM_014450 NP_055265.1

SIT1 Antibody, gp30/40 Antibody, RP11-331F9.5 Antibody, SIT-R Antibody, SIT Antibody


Specifications

Target
Human SIT1
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG1 Monoclonal [SIT-01]
Conjugations
Phycoerythrin. Also available Unconjugated.
Purification
Protein A purified
Modifications
Unmodified
Applications
  • Flow Cytometry (1:50)
  • (applications tested for the base form of this product only)
Immunogen
SIT1 antibody was raised against bacterially produced recombinant intracellular fragment of human SIT.
Epitope
Intracellular
Specificity
Reacts with SHP2-interacting transmembrane adaptor protein (SIT) expressed exclusively in lymphoid organs. It weakly cross-reacts with mouse SIT.
Usage
The reagent is designed for Flow Cytometry analysis (see application note on <u>www.exbio.cz</u>). Suggested working dilution is 1:50. Indicated dilution is recommended starting point for use of this product. Working concentrations should be determined by The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
Presentation
PBS, 15 mM sodium azide
Storage
Store at 4°C. Do not freeze. Protect from light.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/25/2018

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