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Anti-SIRT6 / Sirtuin 6 Antibody (aa56-105) IHC-plus™ LS-B5589

Note: This antibody replaces LS-C30854

Ordering

Wt. Vol. Conc. Price
100 µg - 1 mg/ml $395
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular SIRT6 / Sirtuin 6 Antibodies

Anti-SIRT6 / Sirtuin 6 Antibody (aa250-334) LS-C49020
Rabbit Polyclonal to Mouse SIRT6 / Sirtuin 6
Mouse
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image
Anti-SIRT6 / Sirtuin 6 Antibody (aa56-105) IHC-plus™ LS-B5589
Rabbit Polyclonal (IgG) to Human SIRT6 / Sirtuin 6
Human, Monkey, Mouse, Bat, Dog, Hamster, Pig
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image
Anti-SIRT6 / Sirtuin 6 Antibody (C-Terminus) IHC-plus™ LS-B5588
Rabbit Polyclonal to Human SIRT6 / Sirtuin 6
Human, Rat, Bovine, Dog
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal (IgG) to Human SIRT6 / Sirtuin 6
Human, Monkey, Mouse, Bat, Dog, Hamster, Pig
IHC - Paraffin, Western blot (applications tested for the base form of this product only)
Unconjugated

Details

Human SIRT6 / Sirtuin 6
Rabbit
Human, Monkey, Mouse, Bat, Dog, Hamster, Pig (tested or 100% immunogen sequence identity)
Rat, Bovine, Guinea pig, Horse (at least 90% immunogen sequence identity)
IgG Polyclonal
Unconjugated. Also available conjugated with Biotin, FITC, HRP.
Protein A purified
Unmodified

Applications

  • IHC - Paraffin (10 µg/ml)
  • Western blot (1.25 µg/ml)
  • (applications tested for the base form of this product only)

Specificity and Use

SIRT6 / Sirtuin 6 antibody was raised against synthetic peptide located between aa56-105 of human SIRT6 (Q8N6T7, NP_057623). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Monkey, Galago, Marmoset, Mouse, Hamster, Elephant, Dog, Bat, Pig, Opossum (100%); Gibbon, Rat, Bovine, Horse, Guinea pig, Platypus (92%); Turkey, Zebra finch, Chicken, Xenopus (84%).
LS-E11351 - Lyophilized - 100 µg - $145.00
aa56-105
Human SIRT6

Packaging

Lyophilized from PBS with 2% sucrose
Distilled water
Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year); Short term (less than one week): +4°C. Avoid repeat freeze-thaw cycles.
For research use only.

About SIRT6 / Sirtuin 6

Q8N6T7 NM_016539 NP_057623.2

SIRT6 Antibody, SIR2-like protein 6 Antibody, Sirtuin type 6 Antibody, SIR2L6 Antibody, Sir2-related protein type 6 Antibody, Sirtuin 6 Antibody

NAD-dependent protein deacetylase. Has deacetylase activity towards histone H3K9Ac and H3K56Ac. Modulates acetylation of histone H3 in telomeric chromatin during the S-phase of the cell cycle. Deacetylates histone H3K9Ac at NF-kappa-B target promoters and may down-regulate the expression of a subset of NF-kappa-B target genes. Acts as a corepressor of the transcription factor HIF1A to control the expression of multiple glycolytic genes to regulate glucose homeostasis.

Immunohistochemistry

Immunohistochemistry
Anti-SIRT6 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B5589 concentration 10 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Western blot
HepG2 Cell Lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Requested From: United States
Date Requested: 12/9/2016

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