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Anti-SIRT6 / Sirtuin 6 Antibody (aa305-320) IHC-plus™ LS-B900

Note: This antibody replaces LS-C3192


Wt. Vol. Conc. Price
50 µg - 1 mg/ml $395
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)

Most Popular SIRT6 / Sirtuin 6 Antibodies

Anti-SIRT6 / Sirtuin 6 Antibody (aa250-334) LS-C49020
Rabbit Polyclonal to Mouse SIRT6 / Sirtuin 6
IHC - Paraffin, Western blot
Immunohistochemistry Image
Anti-SIRT6 / Sirtuin 6 Antibody (C-Terminus) IHC-plus™ LS-B5588
Rabbit Polyclonal to Human SIRT6 / Sirtuin 6
Human, Rat, Bovine, Dog
IHC - Paraffin, Western blot
Immunohistochemistry Image
Anti-SIRT6 / Sirtuin 6 Antibody (aa56-105) IHC-plus™ LS-B5589
Rabbit Polyclonal (IgG) to Human SIRT6 / Sirtuin 6
Human, Monkey, Mouse, Bat, Dog, Hamster, Pig
IHC - Paraffin, Western blot
Immunohistochemistry Image

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Rabbit Polyclonal to Human SIRT6 / Sirtuin 6
IHC - Paraffin, ELISA


Human SIRT6 / Sirtuin 6
Human (tested or 100% immunogen sequence identity)
Protein G purified


  • IHC - Paraffin (10 µg/ml)
  • ELISA (1:1000)

Specificity and Use

SIRT6 / Sirtuin 6 antibody was raised against synthetic peptide from human SIRT6.
Amino acids 305 to 320 of human SIRT6
Immunohistochemistry: LS-B900 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B900 was determined to be 10 ug/ml.


PBS, 0.09% sodium azide.
Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
For research use only.

About SIRT6 / Sirtuin 6

Q8N6T7 NM_016539 NP_057623.2

SIRT6 Antibody, SIR2-like protein 6 Antibody, Sirtuin type 6 Antibody, SIR2L6 Antibody, Sir2-related protein type 6 Antibody, Sirtuin 6 Antibody

NAD-dependent protein deacetylase. Has deacetylase activity towards histone H3K9Ac and H3K56Ac. Modulates acetylation of histone H3 in telomeric chromatin during the S-phase of the cell cycle. Deacetylates histone H3K9Ac at NF-kappa-B target promoters and may down-regulate the expression of a subset of NF-kappa-B target genes. Acts as a corepressor of the transcription factor HIF1A to control the expression of multiple glycolytic genes to regulate glucose homeostasis.


Anti-SIRT6 antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B900 concentration 10 ug/ml.

Requested From: United States
Date Requested: 10/26/2016

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