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SIRT5 / Sirtuin 5

sirtuin 5

NAD-dependent lysine demalonylase and desuccinylase that specifically removes malonyl and succinyl groups on target proteins. Activates CPS1 and contributes to the regulation of blood ammonia levels during prolonged fasting: acts by mediating desuccinylation of CPS1, thereby increasing CPS1 activity in response to elevated NAD levels during fasting. Activates SOD1 by mediating its desuccinylation, leading to reduced reactive oxygen species. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo. Can deacetylate cytochrome c (CYCS) and a number of other proteins in vitro.

Gene Name: sirtuin 5
Family/Subfamily: ADP-Ribosyltransferase , not assigned-ADP-Ribosyltransferase
Synonyms: SIRT5, SIR2L5, Sir2-like 5, SIR2-like protein 5, Sirtuin 5, Sirtuin type 5
Target Sequences: NM_031244 NP_112534.1 Q9NXA8

☰ Filters
Antibodies (93)
Proteins (12)
ELISA Kits (8)
Custom (6)
Over-Expression Lysate (6)
Primary (93)
Recombinant (6)
Sandwich (2)
SIRT5 / Sirtuin 5 (113)
Human (80)
Mouse (24)
Rat (22)
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IHC (33)
IHC-P (18)
WB (87)
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ELISA (18)
IF (15)
IP (3)
Peptide-ELISA (1)
rabbit (71)
mouse (20)
chicken (1)
sheep (1)
Product Group
IHCPlus (3)
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IgG1 (16)
IgG2a (2)
IgG2b (2)
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monoclonal mc (20)
polyclonal pc (73)
OTI 1G5 (2)
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OTI2F1 (2)
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aa37-310 (16)
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SIRT5 / Sirtuin 5 Antibody - Anti-SIRT5 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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SIRT5 / Sirtuin 5 Rabbit anti-Human Polyclonal (aa30-46) Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
50 µg/$460
SIRT5 / Sirtuin 5 Antibody - Anti-SIRT5 antibody IHC of human small intestine, muscularis mucosa. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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SIRT5 / Sirtuin 5 Rabbit anti-Human Polyclonal (aa179-228) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
SIRT5 / Sirtuin 5 Antibody - IHC of paraffin-embedded Human Kidney tissue using anti-SIRT5 mouse monoclonal antibody.
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SIRT5 / Sirtuin 5 Mouse anti-Human Monoclonal (OTI2F1) Antibody
Rat, Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
SIRT5 / Sirtuin 5 Antibody - IHC of paraffin-embedded Human Kidney tissue using anti-SIRT5 mouse monoclonal antibody.
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SIRT5 / Sirtuin 5 Mouse anti-Human Monoclonal (Carrier-free) (OTI2F1) Antibody
Rat, Human
Flo, IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
SIRT5 / Sirtuin 5 Antibody - IHC of paraffin-embedded Human Kidney tissue using anti-SIRT5 mouse monoclonal antibody.
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SIRT5 / Sirtuin 5 Mouse anti-Human Monoclonal (OTI2A11) Antibody
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
SIRT5 / Sirtuin 5 Antibody - IHC of paraffin-embedded Human Kidney tissue using anti-SIRT5 mouse monoclonal antibody.
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SIRT5 / Sirtuin 5 Mouse anti-Human Monoclonal (Carrier-free) (OTI2A11) Antibody
Human
Flo, IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
SIRT5 / Sirtuin 5 Antibody - SIRT5 antibody ARP32391_T100-NP_112534-SIRT5 (sirtuin (silent mating type information regulation 2 homolog) 5 (S. cerevisiae)) Antibody IHC of formalin-fixed, paraffin-embedded human Kidney. Positive label: Epithelial cells of renal tubule indicated with arrows. Antibody concentration 4-8 ug/ml. Magnification 400X.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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SIRT5 / Sirtuin 5 Rabbit anti-Human Polyclonal (aa184-233) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$397
SIRT5 / Sirtuin 5 Antibody
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SIRT5 / Sirtuin 5 Rabbit anti-Mouse Polyclonal (aa37-310) Antibody
Mouse
WB
Unconjugated
100 µl/$311; 200 µl/$355; 500 µl/$499; 1 ml/$571; 2 ml/$777; 5 ml/$1,261
SIRT5 / Sirtuin 5 Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
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SIRT5 / Sirtuin 5 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, IHC-P, IP, WB
Unconjugated
50 µl/$460
SIRT5 / Sirtuin 5 Antibody - Western blot of SIRT5 / Sirtuin 5 antibody.
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SIRT5 / Sirtuin 5 Rabbit anti-Human Polyclonal (aa37-310) Antibody
Human
WB
Unconjugated
100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225
SIRT5 / Sirtuin 5 Antibody - Anti-SIRT5 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY SIRT5.
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SIRT5 / Sirtuin 5 Mouse anti-Human Monoclonal (OTI1A6) Antibody
Human
Flo, IF, WB
Unconjugated
100 µl/$434
SIRT5 / Sirtuin 5 Antibody - Anti-SIRT5 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY SIRT5.
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SIRT5 / Sirtuin 5 Mouse anti-Human Monoclonal (Carrier-free) (OTI1A6) Antibody
Human
Flo, IF, WB
Unconjugated, Carrier-free
100 µg/$511
SIRT5 / Sirtuin 5 Antibody - Immunohistochemistry image of paraffin-embedded human adrenal gland tissue at a dilution of 1:100
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SIRT5 / Sirtuin 5 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
SIRT5 / Sirtuin 5 Antibody - Anti-SIRT5 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY SIRT5.
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SIRT5 / Sirtuin 5 Mouse anti-Human Monoclonal (OTI2C4) Antibody
Human
Flo, IF, WB
Unconjugated
100 µl/$434
SIRT5 / Sirtuin 5 Antibody - Anti-SIRT5 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY SIRT5.
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SIRT5 / Sirtuin 5 Mouse anti-Human Monoclonal (Carrier-free) (OTI2C4) Antibody
Human
Flo, IF, WB
Unconjugated, Carrier-free
100 µg/$511
SIRT5 / Sirtuin 5 Antibody - Anti-SIRT5 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY SIRT5.
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SIRT5 / Sirtuin 5 Mouse anti-Human Monoclonal (OTI1B6) Antibody
Human
Flo, IF, WB
Unconjugated
100 µl/$434
SIRT5 / Sirtuin 5 Antibody - Anti-SIRT5 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY SIRT5.
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SIRT5 / Sirtuin 5 Mouse anti-Human Monoclonal (Carrier-free) (OTI1B6) Antibody
Human
Flo, IF, WB
Unconjugated, Carrier-free
100 µg/$511
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SIRT5 / Sirtuin 5 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IP, WB
Unconjugated
100 µg/$341
SIRT5 / Sirtuin 5 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Tissue Homogenates
1 Plate/$834
SIRT5 / Sirtuin 5 Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SIRT5 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-SIRT5.
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SIRT5 / Sirtuin 5 Mouse anti-Human Monoclonal (OTI 1G9) Antibody
Human
Flo, WB
Unconjugated
100 µl/$434
SIRT5 / Sirtuin 5 Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SIRT5 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-SIRT5.
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SIRT5 / Sirtuin 5 Mouse anti-Human Monoclonal (Carrier-free) (OTI 1G9) Antibody
Human
Flo, WB
Unconjugated, Carrier-free
100 µg/$511
SIRT5 / Sirtuin 5 Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SIRT5 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-SIRT5.
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SIRT5 / Sirtuin 5 Mouse anti-Human Monoclonal (Carrier-free) (OTI 2E12) Antibody
Human
Flo, IF, WB
Unconjugated, Carrier-free
100 µg/$511
SIRT5 / Sirtuin 5 Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SIRT5 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-SIRT5.
Select
SIRT5 / Sirtuin 5 Mouse anti-Human Monoclonal (Carrier-free) (OTI 1G5) Antibody
Human
Flo, IF, WB
Unconjugated, Carrier-free
100 µg/$511
SIRT5 / Sirtuin 5 Antibody - SIRT5 antibody ARP32390_P050-NP_112534-SIRT5 (sirtuin (silent mating type information regulation 2 homolog) 5 (S. cerevisiae)) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human intestine.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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SIRT5 / Sirtuin 5 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$424
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SIRT5 / Sirtuin 5 Rabbit anti-Human Polyclonal (aa263-292) Antibody
Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
Viewing 1-25 of 113 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).