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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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SIRT1 / Sirtuin 1 Antibody (C‑Terminus) LS‑C137090
Sirtuin 1 antibody LS-C137090 is an unconjugated rabbit polyclonal antibody to human Sirtuin 1 (SIRT1). Validated for ELISA and WB.
Catalog
Size
Price
LS-C137090-100
100 µl
Unavailable

Popular SIRT1 / Sirtuin 1 Products

Fetal Thymus Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Horse, Pig, Rabbit, Zebrafish
Applications: Western blot
Anti-SIRT1 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1564 concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Horse, Pig, Rabbit, Zebrafish
Applications: IHC, IHC - Paraffin, Western blot
Immunofluorescence of SIRT1 in rat lung tissue with SIRT1 antibody at 20 µg/mL.
Species: Human, Mouse, Rat
Applications: Immunofluorescence, Western blot, ELISA
Anti-SIRT1 antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4520 concentration 5 ug/ml.
Species: Human
Applications: IHC, IHC - Paraffin, Immunofluorescence, Western blot, ELISA
Anti-SIRT1 antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B8356 dilution 3.75 ug/ml.
Species: Human, Monkey
Applications: IHC, IHC - Paraffin, Western blot, Peptide Enzyme-Linked Immunosorbent Assay

Product Description

Sirtuin 1 antibody LS-C137090 is an unconjugated rabbit polyclonal antibody to human Sirtuin 1 (SIRT1). Validated for ELISA and WB.
About SIRT1 / Sirtuin 1
The SIRT family of genes are highly conserved from prokaryotes to eukaryotes and are involved in diverse processes including transcriptional regulation, cell cycle progression, DNA damage repair and aging. Sirtuins utilize NAD+ as a substrate to catalyze deacetylation of specific acetylated protein and histones. SIRT1 has been shown to be induced by caloric restriction (CR) in several tissues and SIRT1 mediated deacetylase activity attenuates B-amyloid content in the brain during CR. Q96EB6 NM_012238 NP_036370.2

SIRT1 Antibody, SIR2-like protein 1 Antibody, SIR2alpha Antibody, SIR2L1 Antibody, Sirtuin 1 Antibody, Sir2-like 1 Antibody, Sirtuin type 1 Antibody, HSIR2 Antibody, HSIRT1 Antibody


Specifications

Target
Human SIRT1 / Sirtuin 1
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Affinity purified
Modifications
Unmodified
Applications
  • Western blot (1:200 - 1:1000)
  • ELISA (1:5000 - 1:20000)
Immunogen
A peptide from the C terminal residues of human SIRT1 protein
Epitope
C-Terminus
Presentation
PBS, pH 7.4, 0.02% sodium azide
Storage
Store at -20°C for up to 1 year.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Western blot

Western blot

Western blot

Western blot



Requested From: 
Date Requested: 6/24/2018

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