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SIRPB1 / CD172b

signal-regulatory protein beta 1

SIRPB1 / CD172b is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein was found to interact with TYROBP/DAP12, a protein bearing immunoreceptor tyrosine-based activation motifs. This protein was also reported to participate in the recruitment of tyrosine kinase SYK. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene Name: signal-regulatory protein beta 1
Synonyms: SIRPB1, CD172b, SIRP-BETA-1, CD172b antigen, SIRP-beta-1 isoform 3
Target Sequences: NM_006065 NP_006056.2 O00241

Publications (1)

1
Loss of microglial SIRPa promotes synaptic pruning in preclinical models of neurodegeneration. Xin Ding #, Jin Wang # , Miaoxin Huang #, Zhangpeng Chen #, Jing Liu, Qipeng Zhang , Chenyu Zhang, Yang Xiang, Ke Zen, Liang Li. Nature communications. 2021 Apr;12:2030. [Full Text Article] [PubMed:33795678] [PMC:PMC8016980] Related Antibodies: LS-C679465.

☰ Filters
Antibodies (38)
Proteins (15)
ELISA Kits (1)
Over-Expression Lysate (4)
Primary (38)
Recombinant (11)
Sandwich (1)
SIRPB1 / CD172b (54)
Human (31)
Mouse (9)
Rat (1)
Bovine (1)
IHC (2)
IHC-P (1)
WB (34)
Flo (1)
ELISA (13)
IF (2)
IP (1)
Peptide-ELISA (2)
rabbit (33)
mouse (5)
IgG (15)
IgG1 (5)
monoclonal mc (5)
polyclonal pc (33)
B4B6 (1)
OTI3G8 (2)
OTI8C5 (2)
96-Well Strip Plate (1)
APC (2)
APC Conjugated (3)
Azide-free (1)
Biotin Conjugated (4)
Carrier-free (2)
Cy3 Conjugated (2)
Cy7 Conjugated (2)
FITC Conjugated (4)
HRP Conjugated (4)
PE Conjugated (3)
Unconjugated (16)
aa127-356 (8)
aa129-342 (8)
aa107-134 (7)
aa30-398 (4)
200-280 aa, Internal (1)
Internal (1)
aa231-280 (1)
No (53)
Yes (1)
Cell Lysates (1)
Tissue Homogenates (1)
6His, N-terminus (3)
GST (1)
His, C-Terminal (1)
His, N-Terminal (1)
His,C-terminus (2)
His-T7 (1)
Myc-DDK (Flag) (6)
Human (11)
Mouse (2)
293T Cells (2)
E. coli (3)
HEK 293 Cells (5)
Human (1)
Mammalian Cells (2)
Wheat Germ Extract (1)
Yeast (1)
Purified (5)
Low endotoxin level (3)
SIRPB1 / CD172b Antibody - Immunohistochemistry of paraffin-embedded human colon cancer at dilution 1:100
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SIRPB1 / CD172b Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50 µg/$294; 100 µg/$360
SIRPB1 / CD172b Antibody - Western blot of recombinant SIRPB1 / CD172b.
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SIRPB1 / CD172b Rabbit anti-Mouse Polyclonal (aa129-342) Antibody
Mouse
WB
Unconjugated
100 µl/$301; 200 µl/$340; 500 µl/$470; 1 ml/$535; 2 ml/$698; 5 ml/$1,161
SIRPB1 / CD172b Antibody - Western blot of recombinant SIRPB1 / CD172b.
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SIRPB1 / CD172b Rabbit anti-Mouse Polyclonal (aa129-342) (Biotin) Antibody
Mouse
WB
Biotin Conjugated
100 µl/$311; 200 µl/$353; 500 µl/$496; 1 ml/$567; 2 ml/$769; 5 ml/$1,248
SIRPB1 / CD172b Antibody - Western blot of recombinant SIRPB1 / CD172b.
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SIRPB1 / CD172b Rabbit anti-Mouse Polyclonal (aa129-342) (FITC) Antibody
Mouse
WB
FITC Conjugated
100 µl/$338; 200 µl/$392; 500 µl/$573; 1 ml/$698; 2 ml/$936; 5 ml/$1,588
SIRPB1 / CD172b Protein - Recombinant Signal Regulatory Protein Beta 1 By SDS-PAGE
Select
E. coli
His-T7
27.9 kDa
50 µg/$460; 10 µg/$284; 200 µg/$917; 100 µg/$735; 1 mg/$2,037; 500 µg/$1,571; 5 mg/$3,207; 2 mg/$2,225
SIRPB1 / CD172b Protein
Select
E. coli
His, N-Terminal
29.0 kDa
50 µg/$452; 10 µg/$283; 200 µg/$902; 100 µg/$722; 1 mg/$2,016; 500 µg/$1,553; 5 mg/$3,151; 2 mg/$2,204
SIRPB1 / CD172b Antibody - Staining HeLa cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody.
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SIRPB1 / CD172b Rabbit anti-Human Polyclonal Antibody
Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Select
SIRPB1 / CD172b Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$351
Select
SIRPB1 / CD172b Rabbit anti-Human Polyclonal (aa107-134) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
Select
SIRPB1 / CD172b Rabbit anti-Human Polyclonal (aa107-134) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
Select
SIRPB1 / CD172b Rabbit anti-Human Polyclonal (aa107-134) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
Select
SIRPB1 / CD172b Rabbit anti-Human Polyclonal (aa107-134) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
Select
SIRPB1 / CD172b Rabbit anti-Human Polyclonal (aa107-134) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
Select
SIRPB1 / CD172b Rabbit anti-Human Polyclonal (aa107-134) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
Select
SIRPB1 / CD172b Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$357
SIRPB1 / CD172b Antibody - Western blot of CD172b antibody
Select
SIRPB1 / CD172b Rabbit anti-Human Polyclonal (200-280 aa, Internal) Antibody
Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
SIRPB1 / CD172b Antibody - Western blot analysis of lysates from HeLa, COLO, and HUVEC cells, using SIRPB1 Antibody. The lane on the right is blocked with the synthesized peptide.
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SIRPB1 / CD172b Rabbit anti-Human Polyclonal (aa231-280) Antibody
Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
SIRPB1 / CD172b Antibody
Select
SIRPB1 / CD172b Mouse anti-Human Monoclonal (B4B6) Antibody
Human
Flo
Unconjugated
100 µg/$423
SIRPB1 / CD172b Antibody - Western blot analysis of CD172b expression in A375 (A); A549 (B) whole cell lysates.
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SIRPB1 / CD172b Rabbit anti-Human Polyclonal (Internal) Antibody
Bovine, Human
IP, WB
Unconjugated
100 µl/$299
SIRPB1 / CD172b Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control. (Left lane) or pCMV6-ENTRY SIRPB1. (Right lane) cDNA for 48 hrs and lysed
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SIRPB1 / CD172b Mouse anti-Human Monoclonal (aa30-398) (OTI8C5) Antibody
Human
WB
Unconjugated
100 µl/$434
SIRPB1 / CD172b Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control. (Left lane) or pCMV6-ENTRY SIRPB1. (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates. (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-SIRPB1. (1:2000)
Select
SIRPB1 / CD172b Mouse anti-Human Monoclonal (aa30-398) (Carrier-free) (OTI8C5) Antibody
Human
WB
Unconjugated, Carrier-free
100 µg/$511
SIRPB1 / CD172b Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control. (Left lane) or pCMV6-ENTRY SIRPB1. (Right lane) cDNA for 48 hrs and lysed
Select
SIRPB1 / CD172b Mouse anti-Human Monoclonal (aa30-398) (OTI3G8) Antibody
Human
WB
Unconjugated
100 µl/$434
SIRPB1 / CD172b Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control. (Left lane) or pCMV6-ENTRY SIRPB1. (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates. (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-SIRPB1. (1:2000)
Select
SIRPB1 / CD172b Mouse anti-Human Monoclonal (aa30-398) (Carrier-free) (OTI3G8) Antibody
Human
WB
Unconjugated, Carrier-free
100 µg/$511
SIRPB1 / CD172b Antibody - SIRPB1 Antibody western blot of A549 cell line lysates (35 ug/lane). The SIRPB1 antibody detected the SIRPB1 protein (arrow).
Select
SIRPB1 / CD172b Rabbit anti-Human Polyclonal (aa107-134) Antibody
Human
WB
Unconjugated
400 µl/$393
SIRPB1 / CD172b Antibody - Western blot of recombinant SIRPB1 / CD172b.
Select
SIRPB1 / CD172b Rabbit anti-Human Polyclonal (aa127-356) Antibody
Human
WB
Unconjugated
100 µl/$299; 200 µl/$337; 500 µl/$463; 1 ml/$527; 2 ml/$682; 5 ml/$1,141
Viewing 1-25 of 54 product results



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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).