Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Rat Monoclonal [clone 23M14A10] (IgG2a,k) to Mouse Siglech
IHC, IHC - Paraffin, Western blot, Flow Cytometry
Rat Monoclonal [clone 440c] (IgG2b) to Mouse Siglech
IHC, IHC - Frozen, Flow Cytometry, Functional Assay (applications tested for the base form of this product only)
Mouse (tested or 100% immunogen sequence identity)
IgG2b Monoclonal [440c]
Also available conjugated with FITC.
IHC - Frozen
(applications tested for the base form of this product only)
Specificity and Use
Siglech antibody was raised against purified bone-marrow derived mouse IPC
For immunohistology and flow cytometry dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:50. For inhibition of IFN-alpha secretion dilutions have to be made according to the amounts of Siglec-H to be inactivated.