SIGLEC8

sialic acid binding Ig-like lectin 8

Sialic acid-binding immunoglobulin (Ig)-like lectins, or SIGLECs (e.g., CD33 (MIM 159590)), are a family of type 1 transmembrane proteins each having a unique expression pattern, mostly in hemopoietic cells. SIGLEC8 is a member of the CD33-like subgroup of SIGLECs, which are localized to 19q13.3-q13.4 and have 2 conserved cytoplasmic tyrosine-based motifs: an immunoreceptor tyrosine-based inhibitory motif, or ITIM (see MIM 604964), and a motif homologous to one identified in signaling lymphocyte activation molecule (SLAM; MIM 603492) that mediates an association with SLAM-associated protein (SAP; MIM 300490) (summarized by Foussias et al., 2000 [PubMed 11095983]).

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Products

Antibodies (25)

ELISA Kits (9)

Proteins (9)

Type

Over-Expression Lysate (2)

Primary (25)

Recombinant (7)

Sandwich (8)

Sandwich CLIA (1)

Target

SIGLEC8 (43)

Reactivity

Human (29)

Mouse (4)

Rat (2)

Chicken (1)

Monkey (1)

Porcine (1)

Rabbit (1)

Sheep (1)

Application

IHC (9)

IHC-P (2)

WB (25)

ELISA (8)

Peptide-ELISA (1)

Host

rabbit (24)

goat (1)

Isotype

IgG (10)

Clonality

polyclonal pc (25)

Format

12 x 8-Well Microstrips (1)

96-Well Microplate (1)

96-Well Strip Plate (7)

APC (1)

APC Conjugated (2)

Azide-free (1)

Biotin Conjugated (3)

Cy3 Conjugated (1)

Cy7 Conjugated (1)

FITC Conjugated (3)

HRP Conjugated (3)

PE Conjugated (2)

Unconjugated (10)

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Epitope

aa70-336 (8)

aa94-122 (7)

C-Terminus (4)

aa373-406 (2)

aa134-145 (1)

Publications

No (43)

Sample Type

Cell Lysates (1)

Plasma (3)

Serum (3)

Tissue Homogenates (1)

Tag

6His, C-terminus (2)

Fc, C-terminus (1)

GST, N-terminus (1)

His-GST-S (1)

Mouse IgG Fc, C-terminus (1)

Myc-DDK (Flag) (3)

Species

Human (7)

Mouse (1)

Source

293T Cells (1)

E. coli (1)

HEK 293 Cells (2)

Human (4)

Wheat Germ Extract (1)

Low Endotoxin Level

Low endotoxin level (4)

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SIGLEC8 Antibody (aa94-122) LS-C161093

Antibody:

SIGLEC8 Rabbit anti-Human Polyclonal (aa94-122) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

400 µl/$393

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SIGLEC8 Antibody (aa373-406) LS-C97831

Antibody:

SIGLEC8 Rabbit anti-Human Polyclonal (aa373-406) Antibody

Reactivity:

Mouse, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

400 µl/$393

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Human SIGLEC8 (Sandwich ELISA) ELISA Kit - LS-F7719

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates

Price:

1 Plate/$798

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SIGLEC8 Antibody (aa134-145) LS-C87375

Antibody:

SIGLEC8 Goat anti-Human Polyclonal (aa134-145) Antibody

Reactivity:

Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µg/$503

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Human SIGLEC8 (CLIA) ELISA Kit - LS-F29860

Type:

Sandwich CLIA

Format:

12 x 8-Well Microstrips

Reactivity:

Human

Range:

62.5 - 4000 pg/ml

Detection:

Chemiluminescent

Sample Types:

Plasma, Serum

Price:

1 Plate/$728

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Human SIGLEC8 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G71514

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

53.9 kDa

Price:

20 µg/$1,107

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SIGLEC8 Antibody (aa94-122) LS-C330132

Antibody:

SIGLEC8 Rabbit anti-Human Polyclonal (aa94-122) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

200 µl/$734

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SIGLEC8 Antibody (aa94-122, Biotin) LS-C240789

Antibody:

SIGLEC8 Rabbit anti-Human Polyclonal (aa94-122) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

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SIGLEC8 Antibody (aa94-122, FITC) LS-C240791

Antibody:

SIGLEC8 Rabbit anti-Human Polyclonal (aa94-122) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

FITC Conjugated

Price:

200 µl/$952

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SIGLEC8 Antibody (aa94-122, Azide-free, HRP) LS-C248159

Antibody:

SIGLEC8 Rabbit anti-Human Polyclonal (aa94-122) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

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SIGLEC8 Antibody (aa94-122, APC) LS-C240790

Antibody:

SIGLEC8 Rabbit anti-Human Polyclonal (aa94-122) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

APC Conjugated

Price:

200 µl/$952

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SIGLEC8 Antibody (aa94-122, PE) LS-C240794

Antibody:

SIGLEC8 Rabbit anti-Human Polyclonal (aa94-122) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

PE Conjugated

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• HRP, Azide-free
• APC
• PE

• Unconjugated
• Biotin
• FITC
• More...
  • HRP, Azide-free
  • APC
  • PE

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SIGLEC8 Antibody (aa373-406) LS-C328662

Antibody:

SIGLEC8 Rabbit anti-Human Polyclonal (aa373-406) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

200 µl/$734

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SIGLEC8 Antibody LS-C743195

Antibody:

SIGLEC8 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

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SIGLEC8 Antibody LS-C765331

Antibody:

SIGLEC8 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

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SIGLEC8 Antibody LS-C497222

Antibody:

SIGLEC8 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

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SIGLEC8 Antibody (C-Terminus) LS-C345727

Antibody:

SIGLEC8 Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

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SIGLEC8 Antibody (C-Terminus, HRP) LS-C480543

Antibody:

SIGLEC8 Rabbit anti-Human Polyclonal (C-Terminus) (HRP) Antibody

Reactivity:

Human

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

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SIGLEC8 Antibody (C-Terminus, FITC) LS-C480542

Antibody:

SIGLEC8 Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody

Reactivity:

Human

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• FITC

• Unconjugated
• HRP
• FITC

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SIGLEC8 Antibody (aa70-336) LS-C372812

Antibody:

SIGLEC8 Rabbit anti-Human Polyclonal (aa70-336) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$303; 200 µl/$343; 500 µl/$476; 1 ml/$543; 2 ml/$715; 5 ml/$1,182

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SIGLEC8 Antibody (aa70-336, HRP) LS-C710342

Antibody:

SIGLEC8 Rabbit anti-Human Polyclonal (aa70-336) (HRP) Antibody

Reactivity:

Human

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$331; 200 µl/$383; 500 µl/$556; 1 ml/$665; 2 ml/$901; 5 ml/$1,511

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SIGLEC8 Antibody (aa70-336, Biotin) LS-C686337

Antibody:

SIGLEC8 Rabbit anti-Human Polyclonal (aa70-336) (Biotin) Antibody

Reactivity:

Human

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$313; 200 µl/$357; 500 µl/$503; 1 ml/$576; 2 ml/$788; 5 ml/$1,279

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SIGLEC8 Antibody (aa70-336, FITC) LS-C692991

Antibody:

SIGLEC8 Rabbit anti-Human Polyclonal (aa70-336) (FITC) Antibody

Reactivity:

Human

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$341; 200 µl/$397; 500 µl/$583; 1 ml/$715; 2 ml/$953; 5 ml/$1,628

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SIGLEC8 Antibody (aa70-336, PE) LS-C724404

Antibody:

SIGLEC8 Rabbit anti-Human Polyclonal (aa70-336) (PE) Antibody

Reactivity:

Human

Applications:

WB

Format:

PE Conjugated

Price:

100 µl/$396; 200 µl/$476; 500 µl/$815; 1 ml/$969; 2 ml/$1,240; 5 ml/$2,325

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SIGLEC8 Antibody (aa70-336, APC, Cy7) LS-C733395

Antibody:

SIGLEC8 Rabbit anti-Human Polyclonal (aa70-336) (APC, Cy7) Antibody

Reactivity:

Human

Applications:

WB

Format:

APC, Cy7 Conjugated

Price:

100 µl/$489; 200 µl/$614; 500 µl/$1,108; 1 ml/$1,329; 2 ml/$1,860; 5 ml/$3,487

• Unconjugated
• HRP
• Biotin
• FITC
• PE
• APC, Cy7

• Unconjugated
• HRP
• Biotin
• More...
  • FITC
  • PE
  • APC, Cy7

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