SIGLEC7 / CD328

sialic acid binding Ig-like lectin 7

Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,3- and alpha-2,6-linked sialic acid. Also binds disialogangliosides (disialogalactosyl globoside, disialyl lactotetraosylceramide and disialyl GalNAc lactotetraoslylceramide). The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Mediates inhibition of natural killer cells cytotoxicity. May play a role in hemopoiesis. Inhibits differentiation of CD34+ cell precursors towards myelomonocytic cell lineage and proliferation of leukemic myeloid cells (in vitro).

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Products

Antibodies (94)

Proteins (10)

ELISA Kits (5)

Type

Development Kit (1)

Over-Expression Lysate (4)

Primary (94)

Recombinant (6)

Sandwich (4)

Target

SIGLEC7 / CD328 (109)

Reactivity

Human (99)

Mouse (15)

Rat (1)

Bovine (3)

Chimpanzee (3)

Dog (3)

Gibbon (3)

Application

IHC (27)

IHC-Fr (2)

IHC-P (4)

WB (84)

Flo (9)

ELISA (29)

ICC (1)

IF (1)

IP (3)

Peptide-ELISA (1)

Host

rabbit (65)

mouse (29)

Product Group

DevKit DuoPlus (1)

IHCPlus (2)

Isotype

IgG (44)

IgG1 (17)

IgG2b (4)

Clonality

monoclonal mc (29)

polyclonal pc (65)

Clone

5-386 (3)

6-434 (2)

OTI1A1 (2)

OTI1A11 (2)

OTI1A12 (2)

OTI1D11 (2)

OTI1E3 (2)

OTI1G7 (2)

S7.7 (4)

Format

96-Well Strip Plate (4)

Antibody Pair and Standard (1)

APC (4)

APC Conjugated (7)

Azide-free (3)

Biotin Conjugated (11)

Carrier-free (6)

Cy3 Conjugated (4)

Cy7 Conjugated (4)

FITC Conjugated (13)

HRP Conjugated (10)

Low Endotoxin (1)

PE Conjugated (8)

RPE Conjugated (2)

Unconjugated (35)

more less

Epitope

aa18-353 (16)

aa1-30 (14)

aa381-467 (10)

aa38-121 (8)

aa407-438 (7)

aa288-337 (4)

aa290-339 (4)

51-100 aa, Internal (1)

Publications

No (109)

Sample Type

Cell Culture Supernatants (2)

Plasma (5)

Serum (5)

Tissue Homogenates (2)

Tag

6His, C-terminus (1)

GST (1)

GST, N-terminus (1)

His,N-terminus (1)

His-S (2)

Myc-DDK (Flag) (4)

Species

Human (8)

Source

293T Cells (2)

E. coli (3)

HEK 293 Cells (2)

Human (1)

Wheat Germ Extract (2)

Purification

Purified (1)

Low Endotoxin Level

Low endotoxin level (1)

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IHC-plus™ SIGLEC7 / CD328 Antibody (aa1-30) LS-B6906

(4.0) Rating

Antibody:

SIGLEC7 / CD328 Rabbit anti-Human Polyclonal (aa1-30) Antibody

Reactivity:

Mouse, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

200 µl/$460

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SIGLEC7 / CD328 Antibody (clone 5-386) LS-C58033

Antibody:

SIGLEC7 / CD328 Mouse anti-Human Monoclonal (5-386) Antibody

Reactivity:

Human

Applications:

Flo, IHC, IHC-Fr

Format:

Unconjugated

Price:

0.1 mg/$385

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SIGLEC7 / CD328 Antibody (clone 5-386, FITC) LS-C58113

Antibody:

SIGLEC7 / CD328 Mouse anti-Human Monoclonal (FITC) (5-386) Antibody

Reactivity:

Human

Applications:

Flo, IHC, IHC-Fr

Format:

FITC Conjugated

Price:

0.1 mg/$432

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SIGLEC7 / CD328 Antibody (clone 5-386, RPE) LS-C58034

Antibody:

SIGLEC7 / CD328 Mouse anti-Human Monoclonal (RPE) (5-386) Antibody

Reactivity:

Human

Applications:

Flo

Format:

RPE Conjugated

Price:

100 Tests/$485

• Unconjugated
• FITC
• RPE

• Unconjugated
• FITC
• RPE

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SIGLEC7 / CD328 Antibody (clone S7.7, Low Endotoxin) LS-C187561

Antibody:

SIGLEC7 / CD328 Mouse anti-Human Monoclonal (Low Endotoxin) (S7.7) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IP, WB

Format:

Unconjugated, Low Endotoxin

Price:

0.5 mg/$671

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Human SIGLEC7 / CD328 Protein (Recombinant His,N-terminus) (aa18-353) - LS-G14274

Source:

E. coli

Tag:

His,N-terminus

Molecular Weight:

42.4 kDa

Price:

10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119

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SIGLEC7 / CD328 Antibody LS-C502174

Antibody:

SIGLEC7 / CD328 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

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SIGLEC7 / CD328 Antibody (aa18-353, FITC) LS-C418004

Antibody:

SIGLEC7 / CD328 Mouse anti-Human Monoclonal (aa18-353) (FITC) Antibody

Reactivity:

Human

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$348; 200 µl/$408; 500 µl/$608; 1 ml/$758; 2 ml/$996; 5 ml/$1,725

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SIGLEC7 / CD328 Antibody (aa38-121) LS-B14612

Antibody:

SIGLEC7 / CD328 Rabbit anti-Human Polyclonal (aa38-121) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$460

Select

SIGLEC7 / CD328 Antibody (clone S7.7) LS-C187563

Antibody:

SIGLEC7 / CD328 Mouse anti-Human Monoclonal (S7.7) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IP, WB

Format:

Unconjugated

Price:

0.1 mg/$385

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Human SIGLEC7 / CD328 (Sandwich ELISA) ELISA Kit - LS-F39901

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

125 - 8000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$795

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SIGLEC7 / CD328 Antibody LS-C403036

Antibody:

SIGLEC7 / CD328 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

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SIGLEC7 / CD328 Antibody (aa407-438) LS-C328666

Antibody:

SIGLEC7 / CD328 Rabbit anti-Human Polyclonal (aa407-438) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

200 µl/$734

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SIGLEC7 / CD328 Antibody (aa407-438, Azide-free, HRP) LS-C247863

Antibody:

SIGLEC7 / CD328 Rabbit anti-Human Polyclonal (aa407-438) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

• Unconjugated
• HRP, Azide-free

• Unconjugated
• HRP, Azide-free

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SIGLEC7 / CD328 Antibody (aa1-30) LS-C328664

Antibody:

SIGLEC7 / CD328 Rabbit anti-Human Polyclonal (aa1-30) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

200 µl/$734

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SIGLEC7 / CD328 Antibody (aa1-30, Biotin) LS-C245834

Antibody:

SIGLEC7 / CD328 Rabbit anti-Human Polyclonal (aa1-30) (Biotin) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

• Unconjugated
• Biotin

• Unconjugated
• Biotin

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SIGLEC7 / CD328 Antibody (aa1-30) LS-C330656

Antibody:

SIGLEC7 / CD328 Rabbit anti-Human Polyclonal (aa1-30) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

200 µl/$734

Select

SIGLEC7 / CD328 Antibody (aa1-30, Biotin) LS-C245829

Antibody:

SIGLEC7 / CD328 Rabbit anti-Human Polyclonal (aa1-30) (Biotin) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

Select

SIGLEC7 / CD328 Antibody (aa1-30, FITC) LS-C245830

Antibody:

SIGLEC7 / CD328 Rabbit anti-Human Polyclonal (aa1-30) (FITC) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

FITC Conjugated

Price:

200 µl/$952

Select

SIGLEC7 / CD328 Antibody (aa1-30, APC) LS-C245828

Antibody:

SIGLEC7 / CD328 Rabbit anti-Human Polyclonal (aa1-30) (APC) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

APC Conjugated

Price:

200 µl/$952

Select

SIGLEC7 / CD328 Antibody (aa1-30, PE) LS-C245831

Antibody:

SIGLEC7 / CD328 Rabbit anti-Human Polyclonal (aa1-30) (PE) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

PE Conjugated

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• APC
• PE

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • PE

Select

SIGLEC7 / CD328 Antibody LS-C753298

Antibody:

SIGLEC7 / CD328 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$351

Select

SIGLEC7 / CD328 Antibody (aa18-353) LS-C296413

Antibody:

SIGLEC7 / CD328 Rabbit anti-Human Polyclonal (aa18-353) Antibody

Reactivity:

Human

Applications:

ICC, IP, WB

Format:

Unconjugated

Price:

100 µl/$303; 200 µl/$343; 500 µl/$476; 1 ml/$543; 2 ml/$715; 5 ml/$1,182

Select

SIGLEC7 / CD328 Antibody (aa1-30) LS-C97840

Antibody:

SIGLEC7 / CD328 Rabbit anti-Human Polyclonal (aa1-30) Antibody

Reactivity:

Mouse, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

400 µl/$393

Select

SIGLEC7 / CD328 Antibody (aa407-438) LS-C97842

Antibody:

SIGLEC7 / CD328 Rabbit anti-Human Polyclonal (aa407-438) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

400 µl/$393

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