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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

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SIGLEC7 / CD328 Antibody (clone S7.7, FITC) LS‑C187562
CD328 antibody LS-C187562 is an FITC-conjugated mouse monoclonal antibody to CD328 (SIGLEC7) from human, monkey and rhesus monkey. Validated for ELISA, Flow, IP and WB.
Catalog
Size
Price
LS-C187562-100
100 µg (0.1 mg/ml)
Unavailable

Popular SIGLEC7 / CD328 Products

Antibody
Species: Human
Applications: IHC, IHC - Frozen, Flow Cytometry
Peripheral Human Monocytes stained with Mouse anti Human CDw328: RPE. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human
Applications: IHC, IHC - Frozen, Flow Cytometry
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Anti-SIGLEC7 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B6906 concentration 10 ug/ml.
Species: Human, Mouse
Applications: IHC, IHC - Paraffin, Western blot

Product Description

CD328 antibody LS-C187562 is an FITC-conjugated mouse monoclonal antibody to CD328 (SIGLEC7) from human, monkey and rhesus monkey. Validated for ELISA, Flow, IP and WB.
About SIGLEC7 / CD328
Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,3- and alpha-2,6-linked sialic acid. Also binds disialogangliosides (disialogalactosyl globoside, disialyl lactotetraosylceramide and disialyl GalNAc lactotetraoslylceramide). The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. Q9Y286 NM_014385 NP_055200.1

SIGLEC7 Antibody, AIRM-1 Antibody, AIRM1 Antibody, CD328 antigen Antibody, CDw328 Antibody, CD328 Antibody, D-siglec Antibody, QA79 Antibody, SIGLEC-7 Antibody, QA79 membrane protein Antibody


Specifications

Target
Human SIGLEC7 / CD328
Host
Mouse
Reactivity
Human, Monkey, Rhesus monkey (tested or 100% immunogen sequence identity)
Clonality
IgG1 Monoclonal [S7.7]
Conjugations
Fluorescein. Also available Unconjugated.
Purification
Protein G purified
Modifications
Unmodified
Applications
  • Western blot
  • Immunoprecipitation
  • Flow Cytometry
  • ELISA
  • (applications tested for the base form of this product only)
Immunogen
SIGLEC7 / CD328 antibody was raised against siglec-7 3T3 transfected cells.
Specificity
Recognizes human Sialic acid-binding Ig-like lectin 7, otherwise known as CD328, a putative adhesion molecule and member of the Ig superfamily, predominantly expressed by both resting and activated natural killer (NK) cells, and also at lower levels by monocytes, granulocytes, monocyte-derived macrophages and dendritic cells, and a small population of CD8+ memory T cells. Classified as a CD33-related Siglec, Siglec-7 preferentially binds to glycoconjugates containing alpha-2,3- or alpha-2,6-linked sialic acid, and acts as a novel inhibitory receptor for NK cells, mediating the inhibition of NK cell cytotoxicity, and implicated in the regulation of NK cell and T cell activation, and hematopoiesis. Clone S7.7 is a blocking antibody see for details, and has been shown to recognize Siglec-7 in Rhesus monkey see for details.
Usage
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
Presentation
PBS, 0.09% sodium azide, 1% BSA
Storage
4°C or -20°C, Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Flow Cytometry

Human peripheral blood lymphocytes stained with Mouse anti-Human Siglec-7: FITC This image was taken for the unconjugated form of this product. Other forms have not been tested.
Human peripheral blood lymphocytes stained with Mouse anti-Human Siglec-7: FITC This image was taken for the unconjugated form of this product. Other forms have not been tested.

Flow Cytometry

Human peripheral blood lymphocytes stained with Mouse anti-Human Siglec-7: FITC This image was taken for the unconjugated form of this product. Other forms have not been tested.
Human peripheral blood lymphocytes stained with Mouse anti-Human Siglec-7: FITC This image was taken for the unconjugated form of this product. Other forms have not been tested.

Flow Cytometry

Human peripheral blood lymphocytes stained with Mouse anti-Human Siglec-7: FITC This image was taken for the unconjugated form of this product. Other forms have not been tested.
Human peripheral blood lymphocytes stained with Mouse anti-Human Siglec-7: FITC This image was taken for the unconjugated form of this product. Other forms have not been tested.

Flow Cytometry

Human peripheral blood lymphocytes stained with Mouse anti-Human Siglec-7: FITC This image was taken for the unconjugated form of this product. Other forms have not been tested.
Human peripheral blood lymphocytes stained with Mouse anti-Human Siglec-7: FITC This image was taken for the unconjugated form of this product. Other forms have not been tested.


Requested From: 
Date Requested: 6/19/2018

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