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Anti-SIGLEC1 / CD169 / Sialoadhesin Antibody LS-C45080

Catalog Size Price
LS-C45080-100 100 µg (0.5 mg/ml) Unavailable

Most Popular SIGLEC1 / CD169 / Sialoadhesin Antibodies

Anti-SIGLEC1 / CD169 / Sialoadhesin Antibody (clone HSN1 7D2) LS-C91383
Mouse Monoclonal [clone HSN1 7D2] (IgG1) to Human SIGLEC1 / CD169 / Sialoadhesin
Human
IHC - Paraffin, IHC - Frozen, Flow Cytometry, ELISA, Radioimmunoassay
Unconjugated
Anti-SIGLEC1 / CD169 / Sialoadhesin Antibody LS-C124538
Mouse Monoclonal (IgG2a) to Rat SIGLEC1 / CD169 / Sialoadhesin
Rat
IHC - Paraffin, IHC - Frozen, Immunoprecipitation, Flow Cytometry
Unconjugated
Anti-SIGLEC1 / CD169 / Sialoadhesin Antibody (clone 3B11/11) LS-C187491
Mouse Monoclonal [clone 3B11/11] (IgG1) to Pig SIGLEC1 / CD169 / Sialoadhesin
Pig
IHC - Frozen, Western blot, Immunoprecipitation, Flow Cytometry
Unconjugated
Anti-SIGLEC1 / CD169 / Sialoadhesin Antibody (C-Terminus, clone SP213) LS-C210436
Rabbit Monoclonal [clone SP213] (IgG) to Human SIGLEC1 / CD169 / Sialoadhesin
Human
IHC - Paraffin
Unconjugated
Immunohistochemistry Image
Anti-SIGLEC1 / CD169 / Sialoadhesin Antibody (Internal, clone SP216) LS-C210437
Rabbit Monoclonal [clone SP216] (IgG) to Human SIGLEC1 / CD169 / Sialoadhesin
Human
IHC - Paraffin
Unconjugated
Immunohistochemistry Image

100% Guaranteed
Mouse Monoclonal (IgG2a) to Rat SIGLEC1 / CD169 / Sialoadhesin
Rat
IHC - Frozen, Immunoprecipitation, Flow Cytometry
Unconjugated

Details

Rat SIGLEC1 / CD169 / Sialoadhesin
Mouse
Rat (tested or 100% immunogen sequence identity)
IgG2a Monoclonal
Unconjugated
Protein A purified
Unmodified

Applications

  • IHC - Frozen (1:250)
  • Immunoprecipitation
  • Flow Cytometry (1:500)

Specificity and Use

Rat spleen cell homogenate.
Recognizes the rat CD169 cell surface antigen, a 185kD molecule expressed by macrophages, predominately confined to lymphoid organs only. Monocytes and granulocytes are negative. No other cell types are positive. The most conspicuous property of ED3 is it stains marginal zone macrophages and marginal metallophils in the spleen very strongly. Furthermore, macrophages in (auto-immune) diseased tissues express the ED3 antigen. In healthy tissue no expression occurs. CD169 is a receptor for glycoconjugates containing sialic acid.
Flow Cytometry: Use 10 ul of the suggested working dilution to label 10^6 cells in 100 ul. Method sheets are available on request.

Packaging

PBS, pH 7.4, 0.09% sodium azide.
For research use only.

About SIGLEC1 / CD169 / Sialoadhesin

Q9BZZ2 NM_023068 NP_075556.1

SIGLEC1 Antibody, CD169 Antibody, CD169 antigen Antibody, SIGLEC-1 Antibody, Sialoadhesin Antibody, SN Antibody, DJ1009E24.1 Antibody

Acts as an endocytic receptor mediating clathrin dependent endocytosis. Macrophage-restricted adhesion molecule that mediates sialic-acid dependent binding to lymphocytes, including granulocytes, monocytes, natural killer cells, B-cells and CD8 T-cells. Preferentially binds to alpha-2,3-linked sialic acid (By similarity). Binds to SPN/CD43 on T-cells (By similarity). May play a role in hemopoiesis.

Requested From: 
Date Requested: 10/21/2017

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