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Anti-SIGLEC1 / CD169 / Sialoadhesin Antibody (clone 3B11/11) LS-C187491

Note: This antibody replaces LS-C124536

Ordering

Wt. Vol. Conc. Price
100 µg - 1 mg/ml $465
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular SIGLEC1 / CD169 / Sialoadhesin Antibodies

Anti-SIGLEC1 / CD169 / Sialoadhesin Antibody (clone HSN1 7D2) LS-C91383
Mouse Monoclonal [clone HSN1 7D2] (IgG1) to Human SIGLEC1 / CD169 / Sialoadhesin
Human
IHC - Paraffin, IHC - Frozen, Flow Cytometry, ELISA, Radioimmunoassay
Unconjugated
Anti-SIGLEC1 / CD169 / Sialoadhesin Antibody (clone 3B11/11) LS-C187491
Mouse Monoclonal [clone 3B11/11] (IgG1) to Pig SIGLEC1 / CD169 / Sialoadhesin
Pig
IHC - Frozen, Western blot, Immunoprecipitation, Flow Cytometry
Unconjugated

100% Guaranteed 100% Guaranteed
Mouse Monoclonal [clone 3B11/11] (IgG1) to Pig SIGLEC1 / CD169 / Sialoadhesin
Pig
IHC - Frozen, Western blot, Immunoprecipitation, Flow Cytometry (applications tested for the base form of this product only)
Unconjugated

Details

Pig SIGLEC1 / CD169 / Sialoadhesin
Mouse
Pig (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [3B11/11]
Unconjugated. Also available conjugated with FITC.
Protein G purified
Unmodified

Applications

  • IHC - Frozen
  • Western blot
  • Immunoprecipitation
  • Flow Cytometry
  • (applications tested for the base form of this product only)

Specificity and Use

SIGLEC1 / CD169 / Sialoadhesin antibody was raised against porcine alveolar macrophages.
Porcine CD169, also known as sialoadhesin or Siglec-1, a member of the sialic acid binding immunoglobulin-like lectin (Siglec) family. CD169 was originally identified in mice and identified as the sialic acid dependent Sheep erythrocyte receptor. CD169 has subsequently been identified in rat, human and pig. Was originally raised as part of a panel of anti porcine macrophage monoclonal antibodies raised against isolated porcine alveolar macrophages. Immunohistochemical analysis indicated restriction to macrophage populations mainly in the spleen, lymph nodes, liver and Peyer's patches. Originally described as a non phagocytic intercellular adhesion receptor, work on porcine CD169 indicated that it may play a role as a viral adhesion receptor and as a targeted receptor for the delivery of toxins and antigens. Detects a band of approximately 190 kD in alveolar macrophage extracts under non-reducing conditions.

Packaging

PBS, 0.09% sodium azide
+4°C or -20°C, Avoid repeated freezing and thawing.
For research use only.

About SIGLEC1 / CD169 / Sialoadhesin

Q9BZZ2 NM_023068 NP_075556.1

SIGLEC1 Antibody, CD169 Antibody, CD169 antigen Antibody, SIGLEC-1 Antibody, Sialoadhesin Antibody, SN Antibody, DJ1009E24.1 Antibody

Acts as an endocytic receptor mediating clathrin dependent endocytosis. Macrophage-restricted adhesion molecule that mediates sialic-acid dependent binding to lymphocytes, including granulocytes, monocytes, natural killer cells, B-cells and CD8 T-cells. Preferentially binds to alpha-2,3-linked sialic acid (By similarity). Binds to SPN/CD43 on T-cells (By similarity). May play a role in hemopoiesis.

Requested From: United States
Date Requested: 12/8/2016

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