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Anti-SIAH1 Antibody (C-Terminus) LS-C141931


Wt. Vol. Conc. Price
- 500 µl - Unavailable

Most Popular SIAH1 Antibodies

Anti-SIAH1 Antibody (aa191-240) IHC-plus™ LS-B5639
Rabbit Polyclonal (IgG) to Human SIAH1
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Hamster, Horse, Pig, Rabbit, Chicken, Xenopus, Zebrafish
IHC - Paraffin, Western blot
Immunohistochemistry Image
Anti-SIAH1 Antibody (N-Terminus) LS-C144690
Rabbit Polyclonal to Human SIAH1
IHC, Western blot
Anti-SIAH1 Antibody LS-C154758
Rabbit Polyclonal
IHC, Western blot, ELISA

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal (IgG1) to Drosophila SIAH1
Drosophila, Human, Rat, Pig, Zebrafish
Western blot, Immunoprecipitation


Drosophila SIAH1
Drosophila, Human, Rat, Pig, Zebrafish (tested or 100% immunogen sequence identity)
IgG1 Polyclonal
Tissue culture supernatant


  • Western blot (1:500)
  • Immunoprecipitation (1:500)

Specificity and Use

SIAH1 antibody was raised against synthetic peptide made to an C-terminal portion of the drosophila SINA protein (within residues 280-331). [Swiss-Prot# P21461]
Human SIAH 1 and 2 and Drosophila SINA in proliferating cells and stem cells. This does not detect Drosophila SINAH or normal, nondividing cells.


Tissue culture supernatant, 0.1% sodium azide
Store at 4°C. Do not freeze.
For research use only.

About SIAH1

Q8IUQ4 NM_003031 NP_003022.3

SIAH1 Antibody, HSIAH1 Antibody, HUMSIAH Antibody, Siah-1 Antibody, Siah-1a Antibody, Seven in absentia homolog 1 Antibody, SIAH1A Antibody

E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates E3 ubiquitin ligase activity either through direct binding to substrates or by functioning as the essential RING domain subunit of larger E3 complexes.

Western blot

Western blot
SIAH 1/2 Antibody (8G7H12) - Anti-SINA/SIAH monoclonal antibodies recognize both Drosophila SINA and human SIAH. There are two SINA-like E3 ligases, SINA and SINAH, in Drosophila. SINA monoclonal antibody 8G7H12 is highly specific in recognizing both Drosophila SINA and human SIAH proteins but not Drosophila SINAH. Coomassie blue staining patterns of both the wild-type (WT) and dominant negative (PD) forms of affinity-purified recombinant GST-SINA/SINAH/SIAH fusion proteins are shown in the top panel. Protein standards were included and are shown in kD. Cross-reactivity of SINA monoclonal antibody 8G7H12 against Drosophila SINA and SINAH, and human hSIAH-1 and hSIAH-2 proteins were determined. Anti-SINA-C-terminal antibody 8G7H12 recognizes both human SIAH-1 and SIAH-2 protein.

Requested From: 
Date Requested: 3/29/2017

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