order histories, retained contact details for faster checkout, review submissions, and special promotions.
Forgot password?
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Locations
Orders Processing,
Shipping & Receiving,
Warehouse
2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
Production Lab
Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036
Telephone Numbers
Tel: +1 (206) 374-1102
Fax: +1 (206) 577-4565
Contact Us
Additional Contact Details
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Forgot password?
order histories, retained contact details for faster checkout, review submissions, and special promotions.
SHOX2
short stature homeobox 2
SHOX2 is a member of the homeo box family of genes that encode proteins containing a 60-amino acid residue motif that represents a DNA binding domain. Homeo box genes have been characterized extensively as transcriptional regulators involved in pattern formation in both invertebrate and vertebrate species. Several human genetic disorders are caused by aberrations in human homeo box genes. SHOX is a pseudoautosomal homeo box gene that is thought to be responsible for idiopathic short stature and implicated to play a role in the short stature phenotype of Turner syndrome patients. SHOX2 (also called SHOT for SHOX homologous gene on chromosome 3) has two alternatively spliced transcript variants, SHOX2a and SHOX2b, that have identical homeodomains and share a C-terminal 14-amino acid residue motif characteristic for craniofacially expressed homeodomain proteins. The differences between SHOX2a and SHOX2b reside within the N-termini and an alternatively spliced exon in the C termini. SHOX2 maps to 3q25-q26.1 and is considered to be a candidate gene for Cornelia de Lange syndrome.
| Gene Name: | short stature homeobox 2 |
| Synonyms: | SHOX2, Homeobox protein shotb, OG12X, OG12, Short stature homeobox 2, Homeobox protein Og12X, SHOT |
| Target Sequences: | NM_006884 NP_006875.2 O60902 |
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.
