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Anti-SHANK3 Antibody (aa840-857, clone S69-46) LS-C109032

Ordering

Wt. Vol. Conc. Price
100 µg - - $355
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular SHANK3 Antibodies

Anti-SHANK3 Antibody (Internal) LS-C153697
Rabbit Polyclonal to Human SHANK3
Human
IHC, Western blot
Unconjugated
Immunohistochemistry Image
Anti-SHANK3 Antibody (aa1475-1525) LS-C290822
Rabbit Polyclonal to Human SHANK3
Human, Mouse, Rat, Bovine, Dog, Guinea pig, Horse, Rabbit
Western blot, Immunoprecipitation
Unconjugated
Western blot Image

100% Guaranteed 100% Guaranteed
Mouse Monoclonal [clone S69-46] (IgG2b) to Rat SHANK3
Rat, Human, Monkey, Mouse, Bovine, Hamster, Horse
IHC, ICC, Western blot, Immunoprecipitation (applications tested for the base form of this product only)
Unconjugated

Details

Rat SHANK3
Mouse
Rat, Human, Monkey, Mouse, Bovine, Hamster, Horse (tested or 100% immunogen sequence identity)
Rabbit (at least 90% immunogen sequence identity)
IgG2b Monoclonal [S69-46]
Unconjugated. Also available conjugated with AP, Atto 700, APC, Biotin, FITC, PE, Atto 594, PerCP, RPE, SA, Atto 390, Atto 488, Atto 565, Atto 594, Atto 633, Atto 655, Atto 680.
Protein G purified
Unmodified

Applications

  • IHC (0.1 - 1 µg/ml)
  • ICC (0.1 - 1 µg/ml)
  • Western blot (1 - 10 µg/ml)
  • Immunoprecipitation (1 - 10 µg/ml)
  • (applications tested for the base form of this product only)

Specificity and Use

SHANK3 antibody was raised against synthetic peptide amino acids 840-857 PEKLPGSLRKGIPRTKSV) of rat Shank3 (also known as SH3 and multiple ankyrin repeat domains protein 3, proline-rich synapse- associated protein 2, ProSAP2 and SPANK-2, accession number Q9JLU4). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Marmoset, Mouse, Rat, Hamster, Bovine, Horse (100%); Rabbit, Opossum (94%).
aa840-857
Detects ~190 kD protein.

Packaging

PBS, pH 7.4, 50% glycerol, 0.09% sodium azide
Store at -20°C.
For research use only.

About SHANK3

Q9BYB0 NM_001080420 NP_001073889.1

SHANK3 Antibody, DEL22q13.3 Antibody, KIAA1650 Antibody, SPANK-2 Antibody, PROSAP2 Antibody, PSAP2 Antibody, SCZD15 Antibody

Major scaffold postsynaptic density protein which interacts with multiple proteins and complexes to orchestrate the dendritic spine and synapse formation, maturation and maintenance. Interconnects receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors via complexes with GKAP/PSD-95 and HOMER, respectively, and the actin-based cytoskeleton.

Western blot

Western blot
Western blot analysis of Shank3 in rat brain membrane lysates using a 1:1000 dilution of SHANK3 antibody. This image was taken for the unconjugated form of this product. Other forms have not been tested.
 

Requested From: United States
Date Requested: 12/10/2016

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