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Anti-SHANK1 Antibody (clone S22-21) LS-C153135

Ordering

Wt. Vol. Conc. Price
100 µg - - $415
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

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Most Popular SHANK1 Antibodies

Anti-SHANK1 Antibody (aa2031-2044) LS-C2893
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Anti-SHANK1 Antibody LS-C411292
Rabbit Polyclonal (IgG) to Human SHANK1
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Mouse Monoclonal [clone S22-21] (IgG1)
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Details

SHANK1
Mouse
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [S22-21]
Unconjugated
Protein G purified
Unmodified

Applications

  • IHC (0.1 - 1 µg/ml)
  • ICC (0.1 - 1 µg/ml)
  • Immunofluorescence (1 - 10 µg/ml)
  • Western blot (1 - 10 µg/ml)

Specificity and Use

SHANK1 antibody was raised against fusion protein corresponding to aa 469-691 (SH3/PDZ domains) of rat Shank1
Does not react withShank2 or 3. Detects a ~190-220kDa protein (alternative splicevariants). Positive control: Adult rat brain.

Packaging

PBS, pH 7.4; 50% glycerol, 0.09% sodium azide.
Store at -20°C, stable for one year. Avoid repeated freeze thaw cycles.
For research use only.

About SHANK1

Q9Y566 NM_016148 NP_057232.2

SHANK1 Antibody, SPANK-1 Antibody, SSTR-interacting protein Antibody, Synamon Antibody, SSTRIP Antibody

Seems to be an adapter protein in the postsynaptic density (PSD) of excitatory synapses that interconnects receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors via complexes with GKAP/PSD-95 and Homer, respectively, and the actin-based cytoskeleton. Plays a role in the structural and functional organization of the dendritic spine and synaptic junction.

Requested From: United States
Date Requested: 12/8/2016

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