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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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SHANK1 Antibody (aa84‑309) LS‑C124521
Antibody
SHANK1 antibody LS-C124521 is an unconjugated mouse monoclonal antibody to SHANK1 from human and rat. Validated for IHC, IP and WB.
Catalog
Size
Price
LS-C124521-100
100 µg
Unavailable

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Western blot analysis of Shank1 in rat brain membrane lysates using a 1:1000 dilution of SHANK1 antibody.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Rat, Human, Mouse
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Western blot analysis of Shank1 in rat brain membrane lysates using a 1:1000 dilution of SHANK1 antibody.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Rat, Human, Mouse
Applications: IHC, ICC, Immunofluorescence, Western blot, Immunoprecipitation
Western blot analysis of Shank1 in rat brain membrane lysates using a 1:1000 dilution of SHANK1 antibody.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Rat, Human, Mouse
Applications: IHC, ICC, Immunofluorescence, Western blot, Immunoprecipitation

Product Description

SHANK1 antibody LS-C124521 is an unconjugated mouse monoclonal antibody to SHANK1 from human and rat. Validated for IHC, IP and WB.
About SHANK1
Seems to be an adapter protein in the postsynaptic density (PSD) of excitatory synapses that interconnects receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors via complexes with GKAP/PSD-95 and Homer, respectively, and the actin-based cytoskeleton. Plays a role in the structural and functional organization of the dendritic spine and synaptic junction. Q9Y566 NM_016148 NP_057232.2

SHANK1 Antibody, SPANK-1 Antibody, SSTR-interacting protein Antibody, Synamon Antibody, SSTRIP Antibody


Specifications

Target
Rat SHANK1
Host
Mouse
Reactivity
Rat, Human (tested or 100% immunogen sequence identity)
Clonality
IgG1 Monoclonal
Conjugations
Unconjugated
Purification
Protein G purified
Modifications
Unmodified
Applications
  • IHC (0.1 - 1 µg/ml)
  • Western blot (1 - 10 µg/ml)
  • Immunoprecipitation
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
SHANK1 antibody was raised against fusion protein aa 84-309 (SH3/PDZ domains) of rat Shank2 accession number Q9QX74.
Epitope
aa84-309
Specificity
Recognizes Shank1, Shank2, Shank3. Species cross-reactivity: human.
Usage
Suitable for use in Western Blot, Immunoprecipitation, and Immunohistochemistry. Western Blot:1-10 ug/ml. Immunohistochemistry: 0.1-1 ug/ml.
Presentation
PBS, pH 7.4, 50% glycerol, 0.09% sodium azide
Storage
May be stored at 4°C for short-term only. Aliquot to avoid freeze-thaw cycles. Store at -20°C. Aliquots are stable for at least 1 year.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/19/2018

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