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SHANK1

SH3 and multiple ankyrin repeat domains 1

Seems to be an adapter protein in the postsynaptic density (PSD) of excitatory synapses that interconnects receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors via complexes with GKAP/PSD-95 and Homer, respectively, and the actin-based cytoskeleton. Plays a role in the structural and functional organization of the dendritic spine and synaptic junction.

Gene Name: SH3 and multiple ankyrin repeat domains 1
Synonyms: SHANK1, SPANK-1, SSTR-interacting protein, Synamon, SSTRIP
Target Sequences: NM_016148 NP_057232.2 Q9Y566

Publications (1)

1
Autistic-like behaviours and hyperactivity in mice lacking ProSAP1/Shank2. Schmeisser MJ, Ey E, Wegener S, Bockmann J, Stempel AV, Kuebler A, Janssen AL, Udvardi PT, Shiban E, Spilker C, Balschun D, Skryabin BV, Dieck St, Smalla KH, Montag D, Leblond CS, Faure P, Torquet N, Le Sourd AM, Toro R, Grabrucker AM, Shoichet SA, Schmit. Nature. 2012 486:256-60. (WB; Mouse) [PubMed:22699619]

☰ Filters
Antibodies (14)
Primary (14)
SHANK1 (14)
Human (14)
Mouse (11)
Rat (13)
IHC (13)
WB (14)
ELISA (1)
ICC (11)
IF (10)
IP (11)
rabbit (1)
mouse (13)
IgG (1)
IgG1 (13)
monoclonal mc (13)
polyclonal pc (1)
S22-21 (11)
AP Conjugated (1)
APC Conjugated (1)
Atto 390 Conjugated (1)
Atto 488 Conjugated (1)
Atto 594 Conjugated (1)
Biotin Conjugated (1)
FITC Conjugated (1)
PerCP Conjugated (1)
RPE Conjugated (1)
Unconjugated (5)
aa469-691 (12)
aa84-309 (1)
No (14)
SHANK1 Antibody - Adult rat brain membrane
Select
SHANK1 Mouse anti-Human Monoclonal (aa469-691) (S22-21) Antibody
Mouse, Rat, Human
ICC, IF, IHC, WB
Unconjugated
100 µg/$537
SHANK1 Antibody - Western blot analysis of Shank1 in rat brain membrane lysates using a 1:1000 dilution of SHANK1 antibody.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
SHANK1 Mouse anti-Rat Monoclonal (aa469-691) (S22-21) Antibody
Mouse, Rat, Human
ICC, IHC, IP, WB
Unconjugated
100 µg/$442
SHANK1 Antibody - Western blot analysis of Shank1 in rat brain membrane lysates using a 1:1000 dilution of SHANK1 antibody.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
SHANK1 Mouse anti-Rat Monoclonal (aa469-691) (Biotin) (S22-21) Antibody
Mouse, Rat, Human
ICC, IF, IHC, IP, WB
Biotin Conjugated
100 µg/$475
SHANK1 Antibody - Western blot analysis of Shank1 in rat brain membrane lysates using a 1:1000 dilution of SHANK1 antibody.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
SHANK1 Mouse anti-Rat Monoclonal (aa469-691) (FITC) (S22-21) Antibody
Mouse, Rat, Human
ICC, IF, IHC, IP, WB
FITC Conjugated
100 µg/$472
SHANK1 Antibody - Western blot analysis of Shank1 in rat brain membrane lysates using a 1:1000 dilution of SHANK1 antibody.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
SHANK1 Mouse anti-Rat Monoclonal (aa469-691) (Atto 488) (S22-21) Antibody
Mouse, Rat, Human
ICC, IF, IHC, IP, WB
Atto 488 Conjugated
100 µg/$479
SHANK1 Antibody - Western blot analysis of Shank1 in rat brain membrane lysates using a 1:1000 dilution of SHANK1 antibody.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
SHANK1 Mouse anti-Rat Monoclonal (aa469-691) (Atto 390) (S22-21) Antibody
Mouse, Rat, Human
ICC, IF, IHC, IP, WB
Atto 390 Conjugated
100 µg/$479
SHANK1 Antibody - Western blot analysis of Shank1 in rat brain membrane lysates using a 1:1000 dilution of SHANK1 antibody.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
SHANK1 Mouse anti-Rat Monoclonal (aa469-691) (Atto 594) (S22-21) Antibody
Mouse, Rat, Human
ICC, IF, IHC, IP, WB
Atto 594 Conjugated
100 µg/$479
SHANK1 Antibody - Western blot analysis of Shank1 in rat brain membrane lysates using a 1:1000 dilution of SHANK1 antibody.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
SHANK1 Mouse anti-Rat Monoclonal (aa469-691) (APC) (S22-21) Antibody
Mouse, Rat, Human
ICC, IF, IHC, IP, WB
APC Conjugated
100 µg/$478
SHANK1 Antibody - Western blot analysis of Shank1 in rat brain membrane lysates using a 1:1000 dilution of SHANK1 antibody.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
SHANK1 Mouse anti-Rat Monoclonal (aa469-691) (AP) (S22-21) Antibody
Mouse, Rat, Human
ICC, IF, IHC, IP, WB
AP Conjugated
100 µg/$474
SHANK1 Antibody - Western blot analysis of Shank1 in rat brain membrane lysates using a 1:1000 dilution of SHANK1 antibody.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
SHANK1 Mouse anti-Rat Monoclonal (aa469-691) (RPE) (S22-21) Antibody
Mouse, Rat, Human
ICC, IF, IHC, IP, WB
RPE Conjugated
100 µg/$477
SHANK1 Antibody - Western blot analysis of Shank1 in rat brain membrane lysates using a 1:1000 dilution of SHANK1 antibody.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
SHANK1 Mouse anti-Rat Monoclonal (aa469-691) (PerCP) (S22-21) Antibody
Mouse, Rat, Human
ICC, IF, IHC, IP, WB
PerCP Conjugated
100 µg/$478
Select
SHANK1 Mouse anti-Rat Monoclonal (aa84-309) Antibody
Rat, Human
IHC, IP, WB
Unconjugated
100 µg/$665
Select
SHANK1 Mouse anti-Rat Monoclonal (aa469-691) Antibody
Rat, Human
IHC, WB
Unconjugated
100 µg/$665
Select
SHANK1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$341
Viewing 1-14 of 14 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).