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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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SHANK1 Antibody (aa135‑149) LS‑C40620
Note: This antibody replaces LS-C91349, LS-C26256
SHANK1 antibody LS-C40620 is an unconjugated rabbit polyclonal antibody to SHANK1 from human, mouse, rat and other species. Validated for ELISA, IHC and WB.
Antibody
Catalog
Size
Price
LS-C40620-100
100 µg (1 mg/ml)
$275

Popular SHANK1 Products

IHC of mouse retina using LS-2893.
Species: Rat, Human, Mouse
Applications: IHC, Immunofluorescence
Adult rat brain membrane
Species: Human, Mouse, Rat
Applications: IHC, ICC, Immunofluorescence, Western blot
Western blot analysis of Shank1 in rat brain membrane lysates using a 1:1000 dilution of SHANK1 antibody.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Rat, Human, Mouse
Applications: IHC, ICC, Immunofluorescence, Western blot, Immunoprecipitation
Western blot analysis of Shank1 in rat brain membrane lysates using a 1:1000 dilution of SHANK1 antibody.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Rat, Human, Mouse
Applications: IHC, ICC, Immunofluorescence, Western blot, Immunoprecipitation
Western blot analysis of Shank1 in rat brain membrane lysates using a 1:1000 dilution of SHANK1 antibody.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Rat, Human, Mouse
Applications: IHC, ICC, Immunofluorescence, Western blot, Immunoprecipitation

Product Description

SHANK1 antibody LS-C40620 is an unconjugated rabbit polyclonal antibody to SHANK1 from human, mouse, rat and other species. Validated for ELISA, IHC and WB.
About SHANK1
Seems to be an adapter protein in the postsynaptic density (PSD) of excitatory synapses that interconnects receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors via complexes with GKAP/PSD-95 and Homer, respectively, and the actin-based cytoskeleton. Plays a role in the structural and functional organization of the dendritic spine and synaptic junction. Q9Y566 NM_016148 NP_057232.2

SHANK1 Antibody, SPANK-1 Antibody, SSTR-interacting protein Antibody, Synamon Antibody, SSTRIP Antibody


Specifications

Target
Human SHANK1
Host
Rabbit
Reactivity
Human, Monkey, Mouse, Rat, Bovine, Dog, Hamster, Horse, Xenopus (tested or 100% immunogen sequence identity)
Predicted
Zebrafish (at least 90% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC
  • Western blot (1:500 - 1:1000)
  • ELISA
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
SHANK1 antibody was raised against synthetic peptide from human SHANK1. Percent identity by BLAST analysis: Human, Orangutan, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Panda, Dog, Bovine, Horse, Lizard, Xenopus (100%); Stickleback, Pufferfish, Zebrafish (93%); Chicken, Seabass (80%).
Epitope
aa135-149
Specificity
Residues [ERLLREYPQSFEKGV] of the N terminus of the Shank1a protein
Presentation
PBS, 0.02% Sodium Azide
Restrictions
For research use only.

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Requested From: United States
Date Requested: 9/24/2018

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